Protein Alignment Cyp304a1 and Cyp2s1

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_083051.1
• Gene: Cyp2s1 / 74134
• MGIID: 1921384
• Length: 501
• Species: Mus musculus
• Alignment Length: 518
• Identity: 152/518 - (29%)
• Similarity: 244/518 - (47%)
• Gaps: 44/518 - (8%)

  Fly     3 TETLLTICAAVFLCLSYRYAVGRPSGF-PPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKS 66
            |..||.....:.|.||.........|: ||||..:||.|:   :|.:....|:...|.||:.| .
Mouse     6 TWALLLALLLLLLLLSLTLFRTPARGYLPPGPTPLPLLGN---LLQLRPGALYSGLLRLSKKY-G 66

  Fly    67 DIIGLHVGPF-PVAVVHSADGVREILNNQV--FDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQ 128
            .:..:::||: .|.|:...|.|||.|..|.  |.||..|   |..|...|..|:||.:|..||:.
Mouse    67 PVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTL---ATLDKTFDGHGVFFANGERWKQL 128

  Fly   129 RRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEM-VKSGGYRVLLPLLFNPF 192
            |:|.|..|||.|.|:|  :.|.:||.::..:::..:.....|....| :......|:..|:|.
Mouse   129 RKFTLLALRDLGMGKR--EGEELIQAEVQSLVEAFQKTEGRPFNPSMLLAQATSNVVCSLVFG-- 189

  Fly   193 SANAHFYIVYNECLSREEMGKLVKLCQ---MGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKL 254
                 ..:.|::    :|...:::...   :||     :..:|:...:..|:  :.|....:.:|
Mouse   190 -----IRLPYDD----KEFQAVIQAASGTLLGI-----SSPWGQAYEMFSWL--LQPLPGPHTQL 238

  Fly   255 NESNLFVRQFFADFVDKYLDSYE-EGVERNFMDVYIAEM---RRGPGYGFNRDQLIMGLVDFSFP 315
            ......:..|....|.|:...:: .|..|:.:|.::.:|   ::.||..|....|:|.:....|.
Mouse   239 QHHLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQEKQDPGTEFTEKNLLMTVTYLLFA 303

  Fly   316 AFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLV 380
            ....||..:...:..|:.||.|.:||:.|:.:.:|.||.|:|.||..||:|:|.:.|..|:..||
Mouse   304 GTMTIGATIRYALLLLLRYPQVQQRVREELIQELGPGRAPSLSDRVRLPYTDAVLHEAQRLLALV 368

  Fly   381 PSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSL 445
            |..:||.....|...||.:||.|.|.|.:.:...|..::.:|.:|.|.||||.||:| .|.:..|
Mouse   369 PMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRL-RKHEAFL 432

  Fly   446 PFGAGKRLCAGETFARNMLFLVTATMCQHF--DFVLGPNDRLPDLSQNLNGLIISPPDFWLQL 506
            |:..|||:|.||..||..|:|...::.|.|  :....|.|.  .|...::||...||||.|::
Mouse   433 PYSLGKRVCLGEGLARAELWLFFTSILQAFSLETPCPPGDL--SLKPAISGLFNIPPDFQLRV 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	131/450 (29%)
Cyp2s1	NP_083051.1	CYP2	65..491	CDD:410652	132/452 (29%)