Protein Alignment Cyp304a1 and Cyp2c65

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_082467.2
• Gene: Cyp2c65 / 72303
• MGIID: 1919553
• Length: 490
• Species: Mus musculus
• Alignment Length: 518
• Identity: 154/518 - (29%)
• Similarity: 248/518 - (47%)
• Gaps: 51/518 - (9%)

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYK 65
            |:....|.:.....|.||......:....||||..:|:.|:   :|.::.|.:.|:....|:.|
Mouse     1 MVLGVFLGLLLTCLLLLSLWRQNSQRRNLPPGPTPLPIIGN---ILQLDLKDISKSLRNFSKVY- 61

  Fly    66 SDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQ 128
            ..:..|::|..|..|:|..:.|:|..  :.:.|.||.   |..:.|..:...|:.|..|..|||.
Mouse    62 GPVFTLYLGRNPAVVLHGYEAVKEAFTDHGEEFAGRG---VFPVFDKFKKNCGVVFSSGRTWKEM 123

  Fly   129 RRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKS-GGYRVLLPLLF-NP 191
            |||.|..||:||.|||  .:|..|||:...::|.:|.....|.:...:.. ....|:..::| |.
Mouse   124 RRFSLMTLRNFGMGRR--SIEDRIQEEARCLVDELRKTKGEPCDPTFILGCAPCNVICSIVFQNR 186

  Fly   192 FSANAHFYIVYNECLSREEMGKL----VKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYN 252
            |......::.:.:.|: |.:..|    :::|          :::..::..:|. ||        .
Mouse   187 FDYKDQEFLTFLDILN-ENVEILSSPWIQIC----------NNFPAVIDYLPG-RH--------R 231

  Fly   253 KLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEM---RRGPGYGFNRDQLIMGLVDFSF 314
            ||:::..|...:|...|.::.:|.:....|:|:|.::.:|   :..|...|..:.|:....|. |
Mouse   232 KLHKNFAFAEHYFLSKVKQHQESLDINNPRDFIDCFLIKMEQEKHNPKTEFTCENLVFTASDL-F 295

  Fly   315 PA---FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRI 376
            .|   .|:..::.|||:  |:.||.|..:||.|||.|:|..|.|.::||.::|:|:|.:.|..|.
Mouse   296 AAGTETTSTTLRYSLLL--LLKYPEVTAKVQEEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQRY 358

  Fly   377 ETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKL 441
            ..|:|:.:||....|.:...|.|||.|.|:.||.:...|.:.:.:||:|.|..|||..||. .|.
Mouse   359 IDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFPNPEKFDPSHFLDERGKF-KKS 422

  Fly   442 DVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQN--LNGLIISPPDF 502
            |...||..|||:|.||..||..|||...|:.|:|: :..|.| |.||...  .||....||.|
Mouse   423 DYFFPFSTGKRICVGEGLARAELFLFLTTILQNFN-LKSPVD-LKDLDTTPVANGFASVPPKF 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	138/453 (30%)
Cyp2c65	NP_082467.2	CYP2C-like	61..485	CDD:410758	139/455 (31%)