Protein Alignment Cyp304a1 and Cyp2c66

DIOPT Version :9

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001011707.1
• Gene: Cyp2c66 / 69888
• MGIID: 1917138
• Length: 490
• Species: Mus musculus
• Alignment Length: 520
• Identity: 155/520 - (29%)
• Similarity: 250/520 - (48%)
• Gaps: 55/520 - (10%)

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYK 65
            |:....|.:.....|.||......:....||||..:|:.|:   :|.::.|.:.|:....|:.|
Mouse     1 MVLGVFLGLLLTCLLLLSLWKQNSQRRNLPPGPTPLPIIGN---ILQLDLKDISKSLRNFSKVY- 61

  Fly    66 SDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVR--GIFFQDGPLWK 126
            ..:..|::|..|..|:|....|:|.|  :.:.|.||....||     .:.:|  |:.|..|..||
Mouse    62 GPVFTLYLGKKPAVVLHGYKAVKEALIDHGEEFAGRGTFPVA-----DKFIRRCGVVFSSGRTWK 121

  Fly   127 EQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKS-GGYRVLLPLLF- 189
            |.|||.|..||:||.|:|  .:|..:||:...::|.:|.....|.:...:.. ....|:..::|
Mouse   122 EMRRFSLMTLRNFGMGKR--SIEDRVQEEARCLVDELRKTKGVPCDPTFILGCAPCNVICSIVFQ 184

  Fly   190 NPFSANAHFYIVYNECLSREEMGKL----VKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSG 250
            |.|......::.:.:.|: |.:..|    :::|          :::..::..:|. ||
Mouse   185 NRFDYKDQEFLTFIDILN-ENVEILSSPWIQVC----------NNFPAIIDYLPG-RH------- 230

  Fly   251 YNKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEM---RRGPGYGFNRDQLIMGLVDF 312
             .||.::..|.:.:|...|.::.:|.:....|:|:|.::.:|   :..|...|..:.||....|.
Mouse   231 -RKLLKNFDFAKHYFLAKVIQHKESLDINNPRDFIDCFLIKMEQEKHNPKTEFTCENLIFTASDL 294

  Fly   313 SFPA---FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGL 374
             |.|   .|:..::.|||:  |:.||.|..:||.|||.|:|..|.|.::||.::|:|:|.:.|..
Mouse   295 -FAAGTETTSTTLRYSLLL--LLKYPEVTAKVQAEIDCVIGRHRSPCMQDRHSMPYTDAVLHEIQ 356

  Fly   375 RIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCL 439
            |...|:|:.:||....|.:...|.|||.|.|:.||.:...|.:.:.:||:|.|..|||..||. .
Mouse   357 RYIDLLPTSLPHAVTRDVKFREYLIPKGTTVIASLTSVLYDDKEFLNPERFDPSHFLDESGKF-K 420

  Fly   440 KLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQN--LNGLIISPPDF 502
            |.|...||..|||:|.||..||..|||...|:.|:|: :..|.| |.||...  .||.:..||.|
Mouse   421 KSDYFFPFSTGKRICVGEGLARTELFLFLTTILQNFN-LKSPVD-LKDLDTTPVANGFVSVPPKF 483

  Fly   503  502
            Mouse   484  483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	150/491 (31%)
Cyp2c66	NP_001011707.1	p450	30..487	CDD:278495	150/491 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910