Protein Alignment Cyp304a1 and cyp2k18

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_005163790.1
• Gene: cyp2k18 / 393484
• ZFINID: ZDB-GENE-040426-1584
• Length: 503
• Species: Danio rerio
• Alignment Length: 559
• Identity: 157/559 - (28%)
• Similarity: 232/559 - (41%)
• Gaps: 129/559 - (23%)

  Fly     2 ITETLL------TICAAVFLCLSYRYAVGRPSGF------PPGPPKIPLFGSYLFMLIINFKYLH 54
            :.|:||      |:..|:.|.| ..|.|...||.      ||||..:||.|:   :|.::.....
Zfish     3 VVESLLQFASTGTLLGALLLFL-VLYLVSSGSGSQKEGKEPPGPKPLPLLGN---LLTLDLTRAF 63

  Fly    55 KAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREILNN--QVFDGR---PQLFVAAMRDPGQDV 114
            .....||:.| .:|..:::||....|:.....|:|.|.|  :.|..|   |...:.      .|.
Zfish    64 DTFFELSKTY-GNIFQVYLGPKKTVVLVGYKTVKEALVNHAEAFGDREIGPSFRIM------NDE 121

  Fly   115 RGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQE------------------------Q 155
            .||.|.:|..|||.|||.|..|||||.|:|..: |.:|:|                        .
Zfish   122 HGIVFSNGENWKEMRRFALSNLRDFGMGKRGSE-EKIIEEIHHLKGEFDKFEGKPFDTTEPVNYA 185

  Fly   156 LNDMLDLIRNGPKYPH-----------EHEMVKSGG------YRVLLPLLFNPFSANAHFYIVYN 203
            :::::..|..|.::.:           .:|.|:.||      |. :.|.| .||..|... :|.|
Zfish   186 VSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMGLYN-MFPWL-GPFLKNKRI-VVRN 247

  Fly   204 ECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADF 268
            ...||.:|.||:...                                ...||.::  .|.|...|
Zfish   248 IIQSRAQMTKLITAL--------------------------------LETLNPND--PRGFVDSF 278

  Fly   269 VDKYLDSYEEGVERNFMDVYIAEMRRGPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLML 333
            :...|...:.|.:.::               |:.:.|:|.:.:.........|..|...:..:..
Zfish   279 LIHKLSDEKSGKKNSY---------------FHNENLMMNVANLFVAGTDTTGTTLRWGLMLMAK 328

  Fly   334 YPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYR 398
            ||.:..|||.|||.|:| ||.|.:||||.||:|:|.|.|..|...:||.::||....|....||.
Zfish   329 YPQIQDRVQEEIDRVIG-GRQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDITFNGYF 392

  Fly   399 IPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNM 463
            |.|.|.|:|.|.:...|...|..|..|.||.|||..|:. :|.|..:||.||:|:|.||:.||..
Zfish   393 IKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQF-VKRDAFMPFSAGRRICLGESLARME 456

  Fly   464 LFLVTATMCQHFDFVLGP---NDRLPDLSQNLNGLIISP 499
            |||...::.|.:.|...|   .|.| || :.:.|:.::|
Zfish   457 LFLFFTSLLQSYRFTTPPGVSEDEL-DL-KGIVGITLNP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	135/483 (28%)
cyp2k18	XP_005163790.1	cytochrome_P450	73..498	CDD:477761	136/485 (28%)