Protein Alignment Cyp304a1 and cyp2k22

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_956529.1
• Gene: cyp2k22 / 393204
• ZFINID: ZDB-GENE-040426-822
• Length: 503
• Species: Danio rerio
• Alignment Length: 547
• Identity: 155/547 - (28%)
• Similarity: 247/547 - (45%)
• Gaps: 119/547 - (21%)

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRPSG-FPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWY 64
            |:...||     :||.:|| ::..:..| :||||..:||.|:   :.|::.|..:.:...||:.|
Zfish    17 MVVAFLL-----LFLVISY-FSSSKDQGKYPPGPKPLPLLGN---LHILDLKNTYMSLWKLSKQY 72

  Fly    65 KSDIIGLHVGPFPVAVVHSADGVREILNN--QVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKE 127
             ..:..:|:||..|.|:.....|:|.|.|  :.|..|.   ::.:.....:..||.|.:|..|||
Zfish    73 -GPVYTVHMGPRTVVVLSGYKAVKEALVNLSEEFGERD---ISPIFQDFNEGYGIVFSNGENWKE 133

  Fly   128 QRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGG--YRVLLPLLFN 190
            .|||.|..|||||.|::..: ||:.:|            .||..| |:.:.||  :...|||..
Zfish   134 MRRFALSNLRDFGMGKKRGE-ELITEE------------IKYLKE-EIERFGGKPFETKLPLAM- 183

  Fly   191 PFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRN----------ADDYGKML--------SI 237
             ..:|....|||:                  |:|:.|          |::..|::        ::
Zfish   184 -AISNVIALIVYS------------------IRFEYNSPKFHRAIVRANENAKLVGSPSVQLYNM 229

  Fly   238 IPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEE------GVE--------RNFMDVY 288
            .||:|..        .:|:..:         ||...:|:::      |::        |...|.:
Zfish   230 FPWLRLF--------VINQKRV---------VDNVQESFKQIGEIVNGLKKTLNPQSPRGIADKF 277

  Fly   289 IAEMRRGPGYG-----FNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYLML---YPAVLRRVQNEI 345
            :.:.::....|     :|.:..:. .::..|.|  .|...::.|...|:|   ||.:..:|.:||
Zfish   278 LIQQQKDKESGKTDSLYNSNNFLT-TINNLFGA--GIDTTVTTLRWGLLLIAKYPEIQAKVHDEI 339

  Fly   346 DEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLY 410
            |.|:| .|.|...||||||:|:|.|.|..|...::|..:..:...|..|.||.|.|.|.|.|.:.
Zfish   340 DSVIG-ERQPVPGDRKNLPYTDAVIHEIQRFADILPIGLLRQTSCDVHLNGYLIKKGTSVFPLIA 403

  Fly   411 AFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHF 475
            :...|...|..|:.|.|:.||:..|:. :|.|..:|||||:|||.||:.||..|||...::.|||
Zfish   404 SVLRDENEWETPDSFNPKHFLNKQGQF-VKKDAFMPFGAGRRLCIGESLARMELFLFFTSLLQHF 467

  Fly   476 DFVLGP---NDRLPDLSQNLNGLIISP 499
            .|...|   .|.| ||:. :.|..:||
Zfish   468 CFTPPPGVSEDEL-DLTP-VVGFTLSP 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	135/481 (28%)
cyp2k22	NP_956529.1	cytochrome_P450	72..497	CDD:477761	136/483 (28%)