Protein Alignment Cyp304a1 and Cyp2s1

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001100965.1
• Gene: Cyp2s1 / 308445
• RGDID: 1306078
• Length: 499
• Species: Rattus norvegicus
• Alignment Length: 517
• Identity: 155/517 - (29%)
• Similarity: 243/517 - (47%)
• Gaps: 44/517 - (8%)

  Fly     3 TETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSD 67
            |..||.....:.|.|:......| ...||||..:||.|:   :|.:....|:...|.||:.| ..
  Rat     6 TWALLLALLLLLLALTLPRTPAR-GQLPPGPTPLPLLGN---LLQLRPGALYSGFLRLSKKY-GP 65

  Fly    68 IIGLHVGPF-PVAVVHSADGVREILNNQV--FDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQR 129
            :..:|:||: .|.|:...|.:||.|..|.  |.||..|   |..|...|..|:||.:|..||:.|
  Rat    66 VFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTL---ATLDKTFDGHGVFFANGERWKQLR 127

  Fly   130 RFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEM-VKSGGYRVLLPLLFN--- 190
            :|.|..|||.|.|:|  :.|.:|||::.:::...:.....|....| :......|:..|:|.
  Rat   128 KFTLLALRDLGMGKR--EGEELIQEEVQNLVKAFQRTEGRPFNPSMLLAQATSNVVCSLIFGIRL 190

  Fly   191 PFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLN 255
            |:. :..|     :.:.:...|.|     :||     :..:|:...:..|:  :.|....:.:|.
  Rat   191 PYE-DKEF-----QAVIQAASGTL-----LGI-----SSPWGQAYEMFSWL--LQPLPGPHTQLQ 237

  Fly   256 ESNLFVRQFFADFVDKYLD-SYEEGVERNFMDVYIAEM---RRGPGYGFNRDQLIMGLVDFSFPA 316
            .....:..|....|.::.. |:..|..|:.:|.::.:|   :..||..|....|:|.:....|..
  Rat   238 HHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQEKEDPGTEFTEKNLLMTVTYLLFAG 302

  Fly   317 FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVP 381
            ...||..:...:..|:.||.|.:||:.|:.:.:|..|.|:|.||..||:|:|.:.|..|:..|||
  Rat   303 TMTIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVP 367

  Fly   382 SDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLP 446
            ..:||...:.|...||.:||.|.|.|.:.:...|..::.:||:|.|.||||.||:: .|.:..||
  Rat   368 MGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRI-RKHEAFLP 431

  Fly   447 FGAGKRLCAGETFARNMLFLVTATMCQHF--DFVLGPNDRLPDLSQNLNGLIISPPDFWLQL 506
            :..|||:|.||..||..|:|...::.|.|  |....|.|.  .|...:.||...||||.||:
  Rat   432 YSLGKRVCLGEGLARAELWLFFTSILQAFSLDTPCPPGDL--SLKPAVRGLFNIPPDFQLQV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	134/450 (30%)
Cyp2s1	NP_001100965.1	CYP2	63..489	CDD:410652	135/452 (30%)