Protein Alignment Cyp304a1 and Cyp2d5

DIOPT Version :9

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_775426.1
• Gene: Cyp2d5 / 286963
• RGDID: 628630
• Length: 504
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 141/498 - (28%)
• Similarity: 221/498 - (44%)
• Gaps: 56/498 - (11%)

  Fly    27 SGFPPGPPKIPLFGSYLFMLIINFKY-LHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVREI 90
            |.:||||...|:.|:.|.:...|..| ::|    |...| .|:..|.:|..|:.:|:....|:|:
  Rat    34 SRYPPGPVPWPVLGNLLQVDPSNMPYSMYK----LQHRY-GDVFSLQMGWKPMVIVNRLKAVQEV 93

  Fly    91 LNNQVFD--GRPQLFV---AAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLEL 150
            |.....|  .||.:.:   ..::...|.|  :|...||.|:|||||.:..||.||.|::  .||.
  Rat    94 LVTHGEDTADRPPVPIFKCLGVKPRSQGV--VFASYGPEWREQRRFSVSTLRTFGMGKK--SLEE 154

  Fly   151 VIQEQLNDMLDLI--RNG----PKYPHEHEMVKSGGYRVLLPLLFNPFSANAHFYIVYNECLSRE 209
            .:.::...:.|..  :||    ||     .|:......|:..|:|.........|::....|..|
  Rat   155 WVTKEAGHLCDAFTAQNGRSINPK-----AMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEE 214

  Fly   210 EMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLD 274
               .|:::.                 ..||.:.:.:|.......|.:.....::.|..|:|..|.
  Rat   215 ---SLIEVS-----------------GFIPEVLNTFPALLRIPGLADKVFQGQKTFMAFLDNLLA 259

  Fly   275 SYEEGVE-----RNFMDVYIAEMRR---GPGYGFNRDQLIMGLVDFSFPAFTAIGVQLSLLVQYL 331
            ......:     ||..|.::||:.:   .|...||.:.|.|.:||............|:..:..:
  Rat   260 ENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLM 324

  Fly   332 MLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLG 396
            :|||.|.||||.|||||:|..|.|.:.|:.::|:|.|.|.|..|...:.|.::|.....|.|:..
  Rat   325 ILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQD 389

  Fly   397 YRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFAR 461
            :.|||.|.::.:|.:...|..:|..|.:|.||.||||.|.. :|.:..:||.||:|.|.||..||
  Rat   390 FVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNF-VKHEAFMPFSAGRRACLGEPLAR 453

  Fly   462 NMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPPDFWL 504
            ..|||....:.|||.|.:......|....|. .:.::|..:.|
  Rat   454 MELFLFFTCLLQHFSFSVPAGQPRPSTLGNF-AISVAPLPYQL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	139/493 (28%)
Cyp2d5	NP_775426.1	p450	37..496	CDD:278495	140/495 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000