Protein Alignment Cyp304a1 and cyp2ad2

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_694486.1
• Gene: cyp2ad2 / 259306
• ZFINID: ZDB-GENE-020812-2
• Length: 492
• Species: Danio rerio
• Alignment Length: 520
• Identity: 156/520 - (30%)
• Similarity: 240/520 - (46%)
• Gaps: 71/520 - (13%)

  Fly    13 VFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIGLHVGPFP 77
            |||.::.......||.:||||..:|..|:....:  :||.::|.|....:     :..|.||...
Zfish    21 VFLIIAEMIKNRTPSNYPPGPWPLPFLGTVFTKM--DFKNINKLAKVYGK-----VFSLRVGSEK 78

  Fly    78 VAVVHSADGVREIL--NNQVFDGRP--QLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRD 138
            :.:|.....|:|.|  .|..|..||  .||....:.     .|:...:|.:|:..|||...:||.
Zfish    79 MIIVSGYKMVKEALVTQNDSFVLRPPVPLFHKVYKG-----IGLTMSNGYIWRSHRRFAASHLRT 138

  Fly   139 FGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGY-RVLLPLLFNP-FSANAHFYIV 201
            ||.|::  .|||.||::...:.|..: ..|.|.....:..|.. ..:..|.|.. |..|..:|
Zfish   139 FGEGKK--NLELGIQQECVYLCDAFK-AEKEPFNPIFILHGAVSNTVACLTFGQRFDYNDEWY-- 198

  Fly   202 YNECLSREEMGKLVKLC-QMG----IQFQRNADDYGKMLSIIPWIRHIWPE---WSGYNKLNESN 258
                   :|:.:|...| |:.    :|.. ||  :.|:|..:|     .|.   :|.|.|:.:|
Zfish   199 -------QEILRLDNQCVQLAGSPRVQLY-NA--FPKLLDYLP-----GPHQKVFSNYKKITQS- 247

  Fly   259 LFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRR---GPGYGFNRDQLIMGLVDFSFPAFTAI 320
                  ..|.:.|:.:.::....|:|:|.|:.||.:   .|..|||.:.||:..:|. ..|.|..
Zfish   248 ------LKDEIIKHREDWDPANPRDFIDNYLTEMEKKKSDPQAGFNIESLIISCLDI-VEAGTET 305

  Fly   321 G---VQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPS 382
            |   ::..||  :::.:|.:.::||.|||.|:|..|.|.|:||.|:|:|||.:.|..|...:||.
Zfish   306 GATTLRWGLL--FMIKFPEIQKKVQAEIDRVIGQSRQPCLDDRVNMPYTEAVLHEIQRFGDVVPL 368

  Fly   383 DVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPF 447
            ..|.:|..||::..|.|||.|.:..:|.:...|...|..|:.|.|..|||.:|:. .|.|..|||
Zfish   369 GFPKQAAVDTKIGNYFIPKGTSITTNLSSVLHDPNEWETPDTFNPGHFLDKNGQF-RKRDAFLPF 432

  Fly   448 GAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLI---ISPPDFWLQLQDR 509
            .||||.|.||..|||:|||...::.|.|..     .:.|....:|.|.|   .:|..|.:.:..|
Zfish   433 SAGKRACVGELLARNVLFLFFTSLLQQFTL-----SKCPGEEPSLEGEIWFTYAPAPFRISVSVR 492

  Fly   510  509
            Zfish   493  492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	140/460 (30%)
cyp2ad2	NP_694486.1	cytochrome_P450	66..487	CDD:477761	140/466 (30%)