Protein Alignment Cyp304a1 and Cyp2c39

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_034133.2
• Gene: Cyp2c39 / 13098
• MGIID: 1306818
• Length: 490
• Species: Mus musculus
• Alignment Length: 521
• Identity: 152/521 - (29%)
• Similarity: 260/521 - (49%)
• Gaps: 59/521 - (11%)

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYK 65
            ::|..:||:.:.:.|.| :|.:.||.| .||||...|:.|::   |.|:.|.:.::....|:.|
Mouse     3 LVTFLVLTLSSLILLSL-WRQSCGRGS-LPPGPTPFPIIGNF---LQIDIKNVSQSLTNFSKAY- 61

  Fly    66 SDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQ 128
            ..:..|::|..|..|:|..:.|:|.|  :.:.|..|..:.:....:.|   .||.|.:|..|||.
Mouse    62 GPVFTLYLGSRPTVVLHGYEAVKEALIDHGEEFSDRGSIPMVEKINNG---LGIVFSNGNRWKEI 123

  Fly   129 RRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKS-GGYRVLLPLLFNPF 192
            |||.|..||:.|.|:|  .:|..:||:...:::.:|.....|.:...:.| ....|:..::|.
Mouse   124 RRFTLTTLRNLGMGKR--NIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQ-- 184

  Fly   193 SANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNES 257
              :...|...:..:..|::.:.||:  :...:.:..:::..::...|...|         |:.::
Mouse   185 --DRFDYKDKDFLMLMEKLNENVKI--LSSPWLQVCNNFPLLIDYCPGSHH---------KVLKN 236

  Fly   258 NLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGPGYGFNRDQLIMGLVDFS--------- 313
            ..::|.:..:.:.::.:|.:....|:|:|.|:.:.::.     |..|    ..:||
Mouse   237 VKYIRSYLLEKIKEHQESLDVTNPRDFIDYYLIKQKQA-----NHIQ----QAEFSLENLACTIN 292

  Fly   314 --FPA---FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREG 373
              |.|   .|:..::.:||:  ||.||.|..:||.|||.|:|..|.|.::||.::|:|:|.|.|.
Mouse   293 NLFAAGTETTSTTLRYALLL--LMKYPDVTAKVQEEIDHVIGRHRSPCMQDRNHMPYTDAMIHEV 355

  Fly   374 LRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLC 438
            .|...|||:::|.....|.:...|.|||.|.||.||.:...|::.:.:||.|.|..||||:|..
Mouse   356 QRFINLVPNNIPRAVTCDIKFRNYLIPKGTTVVTSLTSVLHDSKEFPNPELFDPGHFLDANGNF- 419

  Fly   439 LKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDF--VLGPNDRLPDLSQNLNGLIISPPD 501
            .|.|..:||.||||:||||..||..|||...|:.|:|..  ::.|.|  .|:...:||||..||.
Mouse   420 KKSDHFMPFSAGKRVCAGEGLARMELFLFLTTILQNFKLKSLVHPKD--IDMIPFVNGLIALPPH 482

  Fly   502 F 502
            :
Mouse   483 Y 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	132/456 (29%)
Cyp2c39	NP_034133.2	CYP2C-like	61..485	CDD:410758	133/458 (29%)