Protein Alignment Cyp304a1 and Cyp2c37

DIOPT Version :9

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_034131.2
• Gene: Cyp2c37 / 13096
• MGIID: 1306806
• Length: 490
• Species: Mus musculus
• Alignment Length: 516
• Identity: 145/516 - (28%)
• Similarity: 245/516 - (47%)
• Gaps: 54/516 - (10%)

  Fly     6 LLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIG 70
            |:...:.:||...:|.:..| ...||||..:|:.|:   :|.|:.|.:.::...||:.| ..:..
Mouse     7 LVLTLSCLFLLSLWRQSSER-GKLPPGPTPLPIIGN---ILQIDVKDICQSFTNLSKVY-GPVYT 66

  Fly    71 LHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFIL 133
            |::|..|..|:|..:.|:|.|  :.:.|.||.:..|.   |...:..|:.|..|.:||..|||.|
Mouse    67 LYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRFPVF---DKATNGMGLAFSKGNVWKNTRRFSL 128

  Fly   134 RYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSANAHF 198
            ..||:.|.|:|  .:|..:||:...:::            |:.|:.|.......:......|...
Mouse   129 MTLRNLGMGKR--SIEDRVQEEARCLVE------------ELRKTNGSPCDPTFILGCAPCNVIC 179

  Fly   199 YIVYNECL---SREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIR--HIWPEWSGYNKLNESN 258
            .|::.:..   .|:.:..:.||           ::..|:|| .||::  :.:|....|...:...
Mouse   180 SIIFQDRFDYKDRDFLNLMEKL-----------NEITKILS-SPWLQICNTYPALLDYCPGSHKQ 232

  Fly   259 LF-----VRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGPGYG--FNR-DQLIMGLVDFSFP 315
            .|     ::.|..:.:.::.:|.:..:.|:|:|.::....:..|..  .|| :.|.:.:.|....
Mouse   233 FFKNYASIKNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQEDGNQPLQNRLEHLAITVTDLFSA 297

  Fly   316 AFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLV 380
            ........|...:..|:.||.|..:||.||:.|:|..|.|.::||..:|:|:|.|.|..|...|:
Mouse   298 GTETTSTTLRYAILLLLKYPHVTAKVQEEIEHVIGKHRSPCMQDRSRMPYTDAMIHEVQRFIDLI 362

  Fly   381 PSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSL 445
            |:.:||:...|.:...|.|||.|.|:.||.:...|:..:.:||:|.|..|||.:||. .|.|..:
Mouse   363 PNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGKF-KKSDYFI 426

  Fly   446 PFGAGKRLCAGETFARNMLFLVTATMCQHFDF--VLGPNDRLPDLSQNLNGLIISPPDFWL 504
            ||..|||:||||..||..|||...::.|:|:.  ::.|.|  .|::..|.||...||.|.|
Mouse   427 PFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKD--IDVTPMLIGLASVPPAFQL 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	139/490 (28%)
Cyp2c37	NP_034131.2	p450	30..487	CDD:278495	140/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910