DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp304a1 and Cyp2b13

DIOPT Version :9

Sequence 1:	NP_731751.1	Gene:	Cyp304a1 / 41586	FlyBaseID:	FBgn0038095	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	XP_006539571.1	Gene:	Cyp2b13 / 13089	MGIID:	88599	Length:	517	Species:	Mus musculus

Alignment Length:	457	Identity:	135/457 - (29%)
Similarity:	216/457 - (47%)	Gaps:	57/457 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 DIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQLFVA--AMRDPGQDVRGIFFQDGPLWKE 127
            |:..:|:||.||.|:.....:||.|  |.:.|.||..:..|  .|:|     .||||..|..||.
Mouse    90 DVFTVHLGPRPVVVLCGTQTIREALVNNAEAFSGRGTIAAAQLVMQD-----YGIFFSSGERWKT 149

  Fly   128 QRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPF 192
            .|||.|..:::||.|:|  .:|..|:|:...:::            |:.|..|..:.....|...
Mouse   150 LRRFSLATMKEFGMGKR--SVEERIKEEAQCLVE------------ELKKYQGAPLDPTFFFQCV 200

  Fly   193 SANAHFYIVYNECL--SREEMGKLVKL------------CQMGIQFQRNADDYGKMLSIIPWIRH 243
            :||....||:.|..  :.|:..:|:.|            |||   |:.    :..:|...|.:
Mouse   201 TANIICSIVFGERFDYTDEQFLRLLNLMYQIYSLLRSFSCQM---FEL----FSGLLKYFPGV-- 256

  Fly   244 IWPEWSGYNKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRR---GPGYGFNRDQL 305
                   :.::.::...:..|....|:|:..:.:....|:|:|.|:..|.:   .....|:...|
Mouse   257 -------HRQIAKNQQEILNFITHRVEKHRATLDPSEPRDFIDTYLLRMEKEKSNHNTEFHHQNL 314

  Fly   306 IMGLVDFSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATI 370
            :|.::...|.........|......:::||.|..:||.|||:|:|..|||.|:||..:|:|:|.|
Mouse   315 MMSVLSLFFAGTETTSTTLCCGFLLMLMYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVI 379

  Fly   371 REGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADG 435
            .|..|...:||:..||:..:||...||.:||:|.|.|.|.:...|.:.:..|:.|.|:.||||:|
Mouse   380 HEIQRFSDIVPTGAPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDHFLDANG 444

  Fly   436 KLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISPP 500
            .| .|.:..|||..|||:|.||:.|||.|||...::.|:|........:..||:...:|:...||
Mouse   445 AL-KKSEAFLPFSTGKRICLGESIARNELFLFFTSILQNFSVASPVASKDIDLTPKESGIGKIPP 508

  Fly   501 DF 502
            .:
Mouse   509 TY 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	p450	30..504	CDD:278495	135/457 (30%)
Cyp2b13	XP_006539571.1	p450	82..514	CDD:365848	135/457 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S3545
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.860