Protein Alignment Cyp304a1 and Cyp2a12

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_598418.1
• Gene: Cyp2a12 / 13085
• MGIID: 105055
• Length: 492
• Species: Mus musculus
• Alignment Length: 505
• Identity: 135/505 - (26%)
• Similarity: 230/505 - (45%)
• Gaps: 47/505 - (9%)

  Fly     1 MITETLLTICAAVFLCLSYRYAVGRP---SGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSR 62
            |:...||.:....||.:....:|.:.   ...||||..:|..|:|   |.:|.|.::.:...|..
Mouse     1 MLGSGLLLLAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNY---LQLNRKDVYSSITQLQE 62

  Fly    63 WYKSDIIGLHVGPFPVAVVHSADGVREIL--NNQVFDGRPQ------LFVAAMRDPGQDVRGIFF 119
            .| ..:..:|:||..|.|::..|.|:|.|  :.:.|.||.:      ||..         .|:.|
Mouse    63 HY-GPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKG---------YGVAF 117

  Fly   120 QDGPLWKEQRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVL 184
            .:|...|:.|||.:..|||||.|:|  .:|..|||:...::.:::.....|.:
Mouse   118 SNGERAKQLRRFSIATLRDFGMGKR--GVEERIQEEAGCLIKMLQGTCGAPID------------ 168

  Fly   185 LPLLF-NPFSANAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEW 248
             |.:: :..::|....||:.:..:.|:...|..|..||...:..|...|::..:...:....|
Mouse   169 -PTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLP-- 230

  Fly   249 SGYNKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRRGP--GYGFNRDQLIMGLVD 311
            ....::.:.:..:..|....|.:...:.:....|:|:|.::..|::..  ...|:...|:|..::
Mouse   231 GPQQQIIKDSHKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLN 295

  Fly   312 FSFPAFTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRI 376
            ..|.....:...|......||.:|.|..:|..|||.|:|..|.|..||...:|:|:|.|.|..|.
Mouse   296 LFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRF 360

  Fly   377 ETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKL 441
            ....|..:|.:..:||...|:.:||.|.|.|.|.:..:|.:.:|.|:.|.|:.|||..|:| .|:
Mouse   361 SNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQL-KKI 424

  Fly   442 DVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPDLSQN 491
            ...|||..|||.|.|::.|:..|||...|:.|:|.|.. |. :|.|::::
Mouse   425 PAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKF-PR-KLEDINES 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	117/437 (27%)
Cyp2a12	NP_598418.1	CYP2A	64..487	CDD:410761	118/439 (27%)