Protein Alignment Cyp304a1 and cyp2c19

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_002933639.2
• Gene: cyp2c19 / 100494598
• XenbaseID: XB-GENE-6042531
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 512
• Identity: 152/512 - (29%)
• Similarity: 241/512 - (47%)
• Gaps: 83/512 - (16%)

  Fly     7 LTICAAVFLCLSYRYAV----GRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSD 67
            :|:..|:.:||.. |.|    |.|..|||||..:||.|:   :.|:|.|..:...:.|.:.|.|
 Frog    41 ITLFMAIVICLLI-YLVYGGKGTPPNFPPGPKPLPLIGN---LHIMNLKKPYMTLMELGKKYGS- 100

  Fly    68 IIGLHVGPFPVAVVHSADGVREILNN--QVFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRR 130
            :..:.:|...|.|:...|.|::.|.|  :.|..||.:.....|..|   .||.|..|..||..||
 Frog   101 VFSVQLGTEKVVVLCGYDAVKDALINHAEEFSDRPIIEAFHRRSNG---HGITFSHGENWKVMRR 162

  Fly   131 FILRYLRDFGFGRRFDQLELVIQEQLN-DMLDLIRNGPKYPHEHEMVKSGGYRVLLPLLFNPFSA 194
            |.|..|||||.|:|      .|::::| :.:.|:.....|..|                  ||.
 Frog   163 FTLATLRDFGMGKR------TIEDKINEECISLVETFQSYKGE------------------PFE- 202

  Fly   195 NAHFYIVYNECLSREEMGKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHI--------------- 244
                    |..:....:..::....:|.:|:.......|::.:|..|..|
 Frog   203 --------NSLILNAAVANIIVSILLGHRFEYQDPTLLKLIRLINEIARILGTPIVMLYNAYPSV 259

  Fly   245 --WPEWSGYN---KLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYI---AEMRRGPGYGFN 301
              |...|.:|   ...:|:.|:::.||:. ...||..:   :|:|:|.::   :|.:...|..|:
 Frog   260 MRWLPGSHHNVEKNTQKSHTFIKETFAEH-KAQLDIND---QRDFIDAFLIKQSEEKSATGRFFH 320

  Fly   302 RDQLIMGLVDFSFPA---FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNL 363
            .:.|: .|||..|.|   .|:..::.||::  :|.||.:.::||.|||:|:|..: |.:|.||.:
 Frog   321 NENLV-SLVDSLFSAGMETTSTTLRWSLML--MMKYPEIQKKVQEEIDKVIGSAQ-PQMEHRKQM 381

  Fly   364 PFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPE 428
            |:|:|.|.|..|...:||:::||...:|....||.|||.|.|:|.|.:...|...:..|.:|.|:
 Frog   382 PYTDAVIHEIQRFADIVPTNLPHSTTKDVTFRGYLIPKGTQVIPLLTSVLRDKAYFERPYEFYPQ 446

  Fly   429 RFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRL 485
            .|||::|.. :|.:..:||.||||.|||||.|:..|||....:.|:|.|...|...|
 Frog   447 HFLDSEGNF-VKNEAFIPFSAGKRSCAGETLAKMELFLFFTKLLQNFTFQSPPGQDL 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	131/449 (29%)
cyp2c19	XP_002933639.2	cytochrome_P450	98..519	CDD:477761	132/451 (29%)