Protein Alignment Cyp304a1 and cyp2a6

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001120541.1
• Gene: cyp2a6 / 100145695
• XenbaseID: XB-GENE-5903934
• Length: 495
• Species: Xenopus tropicalis
• Alignment Length: 493
• Identity: 146/493 - (29%)
• Similarity: 233/493 - (47%)
• Gaps: 65/493 - (13%)

  Fly     6 LLTICAAVFLCLSYRYAVGRPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIG 70
            ||::|..:.|.|.......:....||||...||.|::   ..|..:.:..:.:.||:.| ..:..
 Frog    10 LLSVCVIILLYLVKWRGKSKSKNLPPGPTAYPLLGNF---PQIGLREIPSSFVQLSKTY-GPVYT 70

  Fly    71 LHVGPFPVAVVHSADGVREILNNQ--VFDGRPQLFVAAMRDPGQDVRGIFFQDGPLWKEQRRFIL 133
            |::|...:.|:...|.|:|.|.:|  ||..|.:|.::.:.   .|..|:...:|..||..|||.|
 Frog    71 LYLGGHRLIVLIGHDAVKEALIDQSDVFSDRGRLGISQVL---FDEHGVIMSNGERWKTMRRFTL 132

  Fly   134 RYLRDFGFGRRFDQLELVIQEQLNDMLDLIRNGPKYPHEHEMVKSGGYRVLLPL-LFNPFSANAH 197
            ..||:||.|:|  .:|..|||:...:.:..|.....|.:             |: |..|..:|..
 Frog   133 TTLRNFGMGKR--SVEERIQEEARSLEEAFRKKKDEPFD-------------PVNLLGPAVSNII 182

  Fly   198 FYIVYNECLSREE---------MGKLVKLCQMGIQFQRNADDYGKMLSIIPWI-RHI-WPEWSGY 251
            ..|::.:....|:         |.:|:.|..         ..:|:::::.|.: :|| .|..:.:
 Frog   183 CSIIFGDRFDYEDEKFTTLLKCMRELINLLN---------SLFGQLVNVFPNLSQHIPGPHQNIF 238

  Fly   252 NKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYIAEM---RRGPGYGFNRDQLIMGLVDFS 313
            ...|:    ::||..|....:.|:.:....|:|:|.::..|   :..|...|:.|.|...:.|..
 Frog   239 TYFNK----IKQFVKDEAKSHKDTLDANCPRDFIDCFLIRMEEEKMNPNTEFHNDNLFAVIFDLF 299

  Fly   314 FPAFTAIGVQL-SLLVQYLML----YPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREG 373
            |     .|.:. ||.::|..|    ||.|..:|..|||:|:|..|.|:.||:..:|:|||.|.|.
 Frog   300 F-----AGTETSSLTLRYAFLIFLKYPEVQEKVYKEIDQVIGQNRYPSFEDKIKMPYTEAVIHEV 359

  Fly   374 LRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLC 438
            .|...:||:.:.||..:||...||.|||.|.|.|.|.:...|.:.:.:|:||.|..|||.:|  |
 Frog   360 QRFADIVPTGLEHKTSKDTTFRGYDIPKGTSVFPVLTSVLKDPKYFKNPDQFDPGHFLDENG--C 422

  Fly   439 LKL-DVSLPFGAGKRLCAGETFARNMLFLVTATMCQHF 475
            .|. |..:||.||||:||||..||..||:...::.|.|
 Frog   423 FKKNDAFMPFSAGKRMCAGEGLARMELFIFLTSILQKF 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	130/433 (30%)
cyp2a6	NP_001120541.1	cytochrome_P450	65..489	CDD:477761	131/435 (30%)