Protein Alignment Cyp304a1 and cyp2k4.4

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001119979.1
• Gene: cyp2k4.4 / 100144933
• XenbaseID: XB-GENE-5768835
• Length: 489
• Species: Xenopus tropicalis
• Alignment Length: 497
• Identity: 155/497 - (31%)
• Similarity: 238/497 - (47%)
• Gaps: 70/497 - (14%)

  Fly     6 LLTICAAVFLCLSYRYAVG---RPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSD 67
            ||::...:||   |:...|   ....|||||..:||.|:   :.|:|.|..|...:.|:..|.|
 Frog     7 LLSVVICIFL---YKVFYGGKETSKNFPPGPKPLPLIGN---LHIMNMKKPHLTFMELAEKYGS- 64

  Fly    68 IIGLHVGPFPVAVVHSADGVREILNN--QVFDGRPQLFVAAMRDPGQDV---RGIFFQDGPLWKE 127
            :.....|.....|:...|.||:.|.|  :.|..|.::.|.      :|:   .||.|..|..||.
 Frog    65 VFSFEFGLRKTVVLCGTDTVRDALINHAEEFSERARIPVF------EDITKGHGIVFAHGENWKV 123

  Fly   128 QRRFILRYLRDFGFGRRFDQLELVIQEQLNDMLDLIR--NGPKYPHEHEMVKSGGYRVLLPLLFN 190
            .|||.|..|||||.|::  .:|..|.|:.:.::::.:  ||..:.:              .|:.|
 Frog   124 MRRFTLSTLRDFGMGKK--TIEDKICEESDCLVEIFKSYNGKPFDN--------------TLIMN 172

  Fly   191 PFSANAHFYIVYNECLSREE--MGKLVKLCQMGIQFQRN--ADDYGKMLSIIPWIRHIWPEWSGY 251
            ...||....|:..:....::  |.||||:....|:....  |..|....||:.||       .|.
 Frog   173 SAVANIIVTILLGDRFDYKDPTMLKLVKVVNQNIRITGGLMARLYNIYPSIMRWI-------PGS 230

  Fly   252 NKLNESNL-----FVRQFFADFVDKYLDSYEEGVERNFMDVYIAEMRR---GPGYGFNRDQLIMG 308
            ::....|:     |:.:.|.:. .|.||..:   :|:.:|.::.:.|.   .....|:.|.|.:
 Frog   231 HQTVSKNMAKVFKFLNETFTEH-RKQLDVND---QRDLIDAFLVKQREEKLSAKTFFHNDNLTV- 290

  Fly   309 LVDFSFPA---FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATI 370
            ||...|.|   .|:..::..||:  :|.||.:.::||.|||:|:|..: |.||.||.:|:|:|.|
 Frog   291 LVTNLFGAGMETTSTTLRWGLLL--MMKYPVIQKKVQKEIDQVIGSAQ-PRLEHRKQMPYTDAVI 352

  Fly   371 REGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADG 435
            .|..|...:.|.::||:..:|....||.|||.|.|:|.|.:...|...:..||:|.||.|||::|
 Frog   353 HEIQRFANIAPINIPHETTQDVTFRGYFIPKGTQVIPVLTSVLQDKAYFKKPEEFYPEHFLDSEG 417

  Fly   436 KLCLKLDVSLPFGAGKRLCAGETFARNMLFLVTATMCQHFDF 477
            |. :|.:..|||.||||.|||||.|:..|||....:.|:|.|
 Frog   418 KF-VKNEAFLPFSAGKRSCAGETLAKMELFLFFTKLLQNFTF 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	135/434 (31%)
cyp2k4.4	NP_001119979.1	cytochrome_P450	62..483	CDD:477761	136/436 (31%)