Protein Alignment Cyp304a1 and cyp2r1

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_001106483.2
• Gene: cyp2r1 / 100127674
• XenbaseID: XB-GENE-1013989
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 139/491 - (28%)
• Similarity: 221/491 - (45%)
• Gaps: 53/491 - (10%)

  Fly    25 RPSGFPPGPPKIPLFGSYLFMLIINFKYLHKAALTLSRWYKSDIIGLHVGPFPVAVVHSADGVRE 89
            :|.|||||||.:||.|:.|.:......|:.|.:.     ....|..|.:|.....|::..|.|:|
 Frog    38 KPRGFPPGPPGLPLIGNILALASDPHVYMKKQSK-----IHGQIFSLDLGGISTVVLNGYDAVKE 97

  Fly    90 ILNNQ--VFDGRPQL-FVAAMRDPGQDVRGIFFQDGPLWKEQRRFILRYLRDFGFGRRFDQLELV 151
            .|..|  ||..||.| ....:.:.|..:...:   |..|.|.|:..:...|.||..::  ..|..
 Frog    98 CLVRQSDVFADRPSLPLFKKLTNMGGLLNAKY---GRCWTEHRKLAVSCFRTFGCSQK--SFESK 157

  Fly   152 IQEQLNDMLDLIRN--GPKYPHEHEMVKSGGYRVLLPLLFNP---FSANAHFYIVYNECLSREEM 211
            |.|:....||.|.:  |.....:| :|......|...:||..   :..|...:::       |..
 Frog   158 ISEECLFFLDAIDSYKGKALDPKH-LVTIAVSNVSNLILFGERFRYDDNDFLHMI-------EIF 214

  Fly   212 GKLVKLCQMGIQFQRNADDYGKMLSIIPWIRHIWPEWSGYNKLNESNLFVRQFFADFVDKYLDSY 276
            .:.::|......|..||   ..::..:|:.:|        .:|..:...|..|....:.::.::.
 Frog   215 SENIELATSAWVFLYNA---FPLIGFLPFGKH--------QQLFRNASEVYDFLLQIIGRFSENR 268

  Fly   277 EEGVERNFMDVYIAEMRRG---PGYGFNRDQLIMGLVDFSFPAFTAIGVQ-----LSLLVQYLML 333
            :....|:|:|.|:.||.|.   |...::.:.||     ||.......|.:     |...:.::.|
 Frog   269 KPQSPRHFIDAYMDEMERNEADPDSTYSMENLI-----FSVGELIIAGTETTTNVLRWAMLFMAL 328

  Fly   334 YPAVLRRVQNEIDEVVGCGRLPNLEDRKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYR 398
            ||.:..:||.|||.|||..|:|..|::..:|:|||.:.|.||...:.|..:.|....||.:.||.
 Frog   329 YPNIQGQVQKEIDGVVGLNRMPTFEEKSRMPYTEAVLHEILRYCNIAPLGIFHATSRDTVVRGYS 393

  Fly   399 IPKDTIVVPSLYAFHSDARIWSDPEQFRPERFLDADGKLCLKLDVSLPFGAGKRLCAGETFARNM 463
            ||:.|.|:.:||:.|.|.:.|:|||.|.||||||:.|:. .|.:..:||..|:|.|.||..||..
 Frog   394 IPEGTTVITNLYSVHFDEKYWTDPEIFYPERFLDSAGQF-TKKEAFVPFSLGRRHCLGEQLARME 457

  Fly   464 LFLVTATMCQHFDFVLGPNDRLPDLSQNLNGLIISP 499
            ::|....:.|.|.... |...:|:|...| |:.:.|
 Frog   458 MYLFFTALLQRFHLHF-PQGFVPNLRPKL-GMTLQP 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	125/450 (28%)
cyp2r1	NP_001106483.2	CYP2R1	62..497	CDD:410754	127/467 (27%)