Protein Alignment Cyp304a1 and cyp1a1

DIOPT Version :10

• Sequence 1: NP_731751.1
• Gene: Cyp304a1 / 41586
• FlyBaseID: FBgn0038095
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_031753360.1
• Gene: cyp1a1 / 100037911
• XenbaseID: XB-GENE-990173
• Length: 566
• Species: Xenopus tropicalis
• Alignment Length: 542
• Identity: 151/542 - (27%)
• Similarity: 244/542 - (45%)
• Gaps: 84/542 - (15%)

  Fly     3 TETLLT--ICAAVFLCL-SYRYAVGRPSGFP--PGPPKIPLFGSYLFMLIINFKYLHKAALTLSR 62
            ||.|:.  :.|.|||.: |.|  |..|.|..  |||...|:.|:.|.:    .|..|.:...:|.
 Frog    59 TEVLVASIVFAIVFLVIRSQR--VKLPPGTKKLPGPMPYPVIGNLLSL----SKNPHLSLTKMSE 117

  Fly    63 WYKSDIIGLHVGPFPVAVVHSADGVREILNNQ--VFDGRPQLFVAAMRDPGQDVRGIFFQD-GPL 124
            .| .|:..:.:|..|:.|:...:.:|:.|..|  .|.|||.||...:...||.:  .|..| |.:
 Frog   118 TY-GDVFQIQIGTKPMLVLSGLETLRQALIRQSDEFAGRPDLFTFRLVGDGQSM--TFSSDSGEV 179

  Fly   125 WKEQRRFILRYLRDFGFGRRFDQLE--LVIQEQLNDMLDLIRNGPKYPHEHEMVKSGG----YRV 183
            |:.:||.....|:.|..........  ||.:..:.:...|||   |:   .|::...|    ||.
 Frog   180 WRARRRLAQNALKTFATSPSPTSSNSCLVEENIITEAEYLIR---KF---KELIDDKGEFDPYRY 238

  Fly   184 LLPLLFNPFSANAHFYIVYNECLSR------EEMGKLVKLCQMGIQFQRNADDYGKMLS------ 236
            ::..:.|         ::...|..:      ||:..:|.|          .|::|...:
 Frog   239 VVVSVAN---------VICGMCFGKRYNHDDEELLNVVNL----------TDEFGAAAASGNPAD 284

  Fly   237 IIPWIRHIWPEWS--GYNKLNESNLFVRQFFADFVDKYLDSYEEGVERNFMDVYI---AEMRRGP 296
            .||.:::: |..|  .:.::|:..|   .|...|..::..::::...|:..|..|   .|.|...
 Frog   285 FIPILQYL-PNSSMKAFKEINQKFL---AFMQKFTKEHYKTFDKNHIRDITDSLIQHSQEKRVDE 345

  Fly   297 GYGFN-RDQLIMGLVDFSFPA-FTAIGVQLSLLVQYLMLYPAVLRRVQNEIDEVVGCGRLPNLED 359
            ..... .::.|:.:|:..|.| |..|...||..:.||:.:|.:.:|:|:|:|:|:|..|.|.|.|
 Frog   346 NSNIQLSNEKIVNIVNDLFGAGFDTITTALSWSLMYLVAHPNIQQRIQDELDQVIGRERRPRLSD 410

  Fly   360 RKNLPFTEATIREGLRIETLVPSDVPHKALEDTELLGYRIPKDTIVVPSLYAFHSDARIWSDPEQ 424
            |..||:|||.|.|..|..:.:|..:||...:||.|.||.|||...|:.:.:..:.|..:|.||.:
 Frog   411 RAQLPYTEAFILEMFRHSSFMPFTIPHCTTKDTMLNGYFIPKGICVLINQWQVNHDPNLWQDPFK 475

  Fly   425 FRPERFLDADGKLCLKLDVS--LPFGAGKRLCAGETFARNMLFLVTATMCQHFDFVLGPNDRLPD 487
            |.|||||:.||.:..|.::.  :.||.|||.|.||...|..:||...||.|...|.....::| |
 Frog   476 FCPERFLNNDGTMVNKTEMEKVMIFGLGKRRCVGEAIGRMEVFLFLTTMLQQMQFFKQDGEKL-D 539

  Fly   488 LSQNLNGLIISPPDFWLQLQDR 509
            :|          |.:.|.::.:
 Frog   540 MS----------PQYGLTMKHK 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp304a1	NP_731751.1	CYP15A1-like	66..504	CDD:410744	128/467 (27%)
cyp1a1	XP_031753360.1	CYP1A	119..555	CDD:410769	130/476 (27%)