DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10909 and fbl

DIOPT Version :9

Sequence 1:	NP_650236.1	Gene:	CG10909 / 41581	FlyBaseID:	FBgn0038090	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	NP_998167.1	Gene:	fbl / 406275	ZFINID:	ZDB-GENE-040426-1936	Length:	317	Species:	Danio rerio

Alignment Length:	234	Identity:	102/234 - (43%)
Similarity:	150/234 - (64%)	Gaps:	3/234 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   109 GTSDRIEPHRHYGVYLLRNRFDAIQLLTRNTSSSADDYGERRVISEYREMRCEFRVWSPFQSKLA 173
            |....:|||||.||::.|.:.||  |:|:|.......|||:|:..|..|.:.|:|.|:||:||||
Zfish    79 GAKVTVEPHRHEGVFICRGKEDA--LVTKNMVIGESVYGEKRINVEEGETKIEYRAWNPFRSKLA 141

  Fly   174 AGIMGGVSDLHLQIGSKVLYLGAGFGRSVSHISDIVGDSGMVYAVEQIPWAGRQLTIMANRRSNI 238
            |.|:||:..:|::.|.||:||||..|.:|||:|||||..|:|||||....:||.|..:|.:|:||
Zfish   142 AAILGGIDQIHIKPGVKVMYLGAASGTTVSHVSDIVGPEGLVYAVEFSHRSGRDLLNVAKKRTNI 206

  Fly   239 VPIVEDATMPYKYRYEVPACIDIIFADLPPSVLIRALMLNARHFLNPGGHFVAYLHSPTSQGVVF 303
            :||:|||..|:|||..| ..:|:||||:......|.:.|||.:||..|||||..:.:........
Zfish   207 IPIIEDARHPHKYRMLV-GMVDVIFADVAQPDQTRIVALNAHNFLKNGGHFVISIKANCIDSTAA 270

  Fly   304 NKDSFAAERRLLKEKQLEPKEMVLLEPFKAGYAFVVGVY 342
            .:..||:|.:.:..:.::|:|.:.|||::..:|.|||:|
Zfish   271 PEAVFASEVKKMSAENMKPQEQLTLEPYERDHAVVVGIY 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10909	NP_650236.1	Fibrillarin	114..344	CDD:279593	101/229 (44%)
fbl	NP_998167.1	PTZ00146	80..316	CDD:240291	101/233 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586791
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1889
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1411035at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10335
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	6	5.810