DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10909 and hectd1

DIOPT Version :9

Sequence 1:	NP_650236.1	Gene:	CG10909 / 41581	FlyBaseID:	FBgn0038090	Length:	349	Species:	Drosophila melanogaster
Sequence 2:	XP_012823549.1	Gene:	hectd1 / 100192372	XenbaseID:	XB-GENE-1010869	Length:	2580	Species:	Xenopus tropicalis

Alignment Length:	129	Identity:	32/129 - (24%)
Similarity:	52/129 - (40%)	Gaps:	22/129 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 ITSKNFENPTKETSIQSPIKNSIKPSWNPEPKITRTSIWDIES----AGGDSIQNDCQ---SECN 90
            :.|..:...|.:...:..:..|:.|......|||...:..||.    |.| ::.:.|:   |:|.
Frog  1979 VASDPYSARTPQEDGEDMLLFSVPPEEFTSKKITTKIVQQIEEPLALASG-ALPDWCEQLTSKCP 2042

  Fly    91 VEDQGHEQEVTLETRIFSGTSDRIEPHRHYGVYLLRNRFDAIQLLTRNTSSSA---DDYGERRV 151
            .       .:..|||....|.......|  .:..|:||.:|  .:.|:.::||   ||.||.||
Frog  2043 F-------LIPFETRQLYFTCTAFGASR--AIVWLQNRREA--TVERSRTASAVRRDDPGEFRV 2095

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10909	NP_650236.1	Fibrillarin	114..344	CDD:279593	14/41 (34%)
hectd1	XP_012823549.1	Ank_2	366..457	CDD:372319
		ANK repeat	366..393	CDD:293786
		PLN03192	<386..612	CDD:215625
		ANK repeat	396..426	CDD:293786
		ANK repeat	428..457	CDD:293786
		F5_F8_type_C	1130..1263	CDD:390053
		MIB_HERC2	1300..1358	CDD:369043
		BTHB	1861..1927	CDD:375836
		HECTc	2101..2578	CDD:238033
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165170892
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930