| Sequence 1: | NP_000520.1 | Gene: | MC2R / 4158 | HGNCID: | 6930 | Length: | 297 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001258645.1 | Gene: | Mc2r / 17200 | MGIID: | 96928 | Length: | 296 | Species: | Mus musculus |
| Alignment Length: | 296 | Identity: | 263/296 - (88%) |
|---|---|---|---|
| Similarity: | 286/296 - (96%) | Gaps: | 0/296 - (0%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MKHIINSYENINNTARNNSDCPRVVLPEEIFFTISIVGVLENLIVLLAVFKNKNLQAPMYFFICS 65
Human 66 LAISDMLGSLYKILENILIILRNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYI 130
Human 131 TIFHALRYHSIVTMRRTVVVLTVIWTFCTGTGITMVIFSHHVPTVITFTSLFPLMLVFILCLYVH 195
Human 196 MFLLARSHTRKISTLPRANMKGAITLTILLGVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQV 260
Human 261 NGMLIMCNAVIDPFIYAFRSPELRDAFKKMIFCSRY 296 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| MC2R | NP_000520.1 | 7tmA_MC2R_ACTH_R | 25..287 | CDD:320472 | 235/261 (90%) |
| TM helix 1 | 26..52 | CDD:320472 | 21/25 (84%) | ||
| TM helix 2 | 59..85 | CDD:320472 | 25/25 (100%) | ||
| TM helix 3 | 103..133 | CDD:320472 | 26/29 (90%) | ||
| TM helix 4 | 145..165 | CDD:320472 | 13/19 (68%) | ||
| TM helix 5 | 170..199 | CDD:320472 | 25/28 (89%) | ||
| TM helix 6 | 212..242 | CDD:320472 | 27/29 (93%) | ||
| TM helix 7 | 255..280 | CDD:320472 | 24/24 (100%) | ||
| Mc2r | NP_001258645.1 | 7tm_4 | 35..291 | CDD:304433 | 228/255 (89%) |
| 7tm_1 | 41..276 | CDD:278431 | 211/234 (90%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83972948 | |
| Domainoid | 1 | 1.000 | 445 | 1.000 | Domainoid score | I9710 |
| eggNOG | 1 | 0.900 | - | - | E33208_3BHT3 | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H444 | |
| Inparanoid | 1 | 1.050 | 553 | 1.000 | Inparanoid score | I11299 |
| Isobase | 1 | 0.950 | - | 0 | Normalized mean entropy | S7194 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG43095 | |
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0012093 | |
| OrthoInspector | 1 | 1.000 | - | - | oto119283 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_118927 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR22750 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R8467 |
| SonicParanoid | 1 | 1.000 | - | - | X9966 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 19 | 19.240 | |||||