DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and STK17A

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_004751.2	Gene:	STK17A / 9263	HGNCID:	11395	Length:	414	Species:	Homo sapiens

Alignment Length:	187	Identity:	38/187 - (20%)
Similarity:	63/187 - (33%)	Gaps:	51/187 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 SQALRELTDGED--------KDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKAL--NEEEFI 83
            |:.|||:....:        .|||:.         ||.:..:|.....|....|..|  :::|..
Human   217 SEELREIMGTPEYVAPEILSYDPISM---------ATDMWSIGVLTYVMLTGISPFLGNDKQETF 272

  Fly    84 TGIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGV 148
            ..|....|..||||       ||.....:::....||..:|                    ||..
Human   273 LNISQMNLSYSEEE-------FDVLSESAVDFIRTLLVKKP--------------------EDRA 310

  Fly   149 ITIQDLKNVY----SVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFV 201
            ...:.||:.:    |::| |.::..:..|:.......|:......:.|...|:|..|
Human   311 TAEECLKHPWLTQSSIQE-PSFRMEKALEEANALQEGHSVPEINSDTDKSETKESIV 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	13/58 (22%)
		EFh	64..119	CDD:238008	12/56 (21%)
		EFh	97..154	CDD:238008	8/56 (14%)
		EF-hand_7	98..158	CDD:290234	9/59 (15%)
		EF-hand_7	134..204	CDD:290234	13/72 (18%)
STK17A	NP_004751.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..40
		STKc_DRAK1	51..321	CDD:271099	29/139 (21%)
		S_TKc	64..321	CDD:214567	29/139 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	342..363		3/20 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900