DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and MEK1

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_014996.3	Gene:	MEK1 / 854533	SGDID:	S000005878	Length:	497	Species:	Saccharomyces cerevisiae

Alignment Length:	179	Identity:	36/179 - (20%)
Similarity:	58/179 - (32%)	Gaps:	81/179 - (45%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RTKGWSLKNPNCDLYTLEANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDD 71
            |.|.:.||  :||:.            ||:.|.:::.|.|.||:               |...||
Yeast   104 RDKTYLLK--HCDVI------------ELSQGSEENDIKKTRLV---------------FMINDD 139

  Fly    72 DGS----KALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSGSI------------------- 113
            ..|    |.|::..|:.       :|.:.||.....     |:|:.
Yeast   140 LQSSLDPKLLDQMGFLR-------EVDQWEITNRIV-----GNGTFGHVLITHNSKERDEDVCYH 192

  Fly   114 --NMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLKNVYSV 160
              |....::||:|              ||.|: |..::...|..|:..|
Yeast   193 PENYAVKIIKLKP--------------NKFDK-EARILLRLDHPNIIKV 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	13/81 (16%)
		EFh	64..119	CDD:238008	13/79 (16%)
		EFh	97..154	CDD:238008	12/77 (16%)
		EF-hand_7	98..158	CDD:290234	13/80 (16%)
		EF-hand_7	134..204	CDD:290234	7/27 (26%)
MEK1	NP_014996.3	FHA	28..122	CDD:238017	8/31 (26%)
MEK1	NP_014996.3	STKc_CAMK	160..443	CDD:270687	15/87 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900