DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10126 and Kalrn

DIOPT Version :9

Sequence 1:NP_788664.2 Gene:CG10126 / 41579 FlyBaseID:FBgn0038088 Length:227 Species:Drosophila melanogaster
Sequence 2:XP_038944566.1 Gene:Kalrn / 84009 RGDID:621865 Length:2989 Species:Rattus norvegicus


Alignment Length:207 Identity:37/207 - (17%)
Similarity:74/207 - (35%) Gaps:39/207 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    17 NCDL--YTLE-----ANMASQALRELTDG----EDKDPITKLRLLCLSRGATGILGLGRAFRAMD 70
            ||.:  ||:|     :.:..|::....|.    ||..|....:....:....||        ::.
  Rat  2600 NCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGI--------SLP 2656

  Fly    71 DDGSKALNEEEFITGIRDTGLDVS-EEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNII 134
            .:.|:.::..|:....  .|..:| :|.....:...:|.|.|..::.:..:. :.......:..:
  Rat  2657 SEPSEFVHLPEYDAAA--DGATISWKENFDSAYTELNEIGRGRFSIVKKCIH-KATRKDVAVKFV 2718

  Fly   135 DQAFNKMDRDEDGVITIQDLKNVYSVKEHPKYQSG-------EKSEDEILTDFLHNFEGGRGNLD 192
            .:...|.::.......:|.|::...|..|..|:|.       |..:|..|.|:|.|.:.      
  Rat  2719 SKKMKKKEQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILELMDDGRLLDYLMNHDE------ 2777

  Fly   193 GKITREEFVNYY 204
               ..||.|.:|
  Rat  2778 ---LMEEKVAFY 2786

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10126NP_788664.2 EF-hand_7 62..119 CDD:290234 8/57 (14%)
EFh 64..119 CDD:238008 8/55 (15%)
EFh 97..154 CDD:238008 5/56 (9%)
EF-hand_7 98..158 CDD:290234 6/59 (10%)
EF-hand_7 134..204 CDD:290234 16/76 (21%)
KalrnXP_038944566.1 SEC14 42..180 CDD:214706
SPEC 193..413 CDD:238103
SPEC 314..539 CDD:238103
SPEC 540..769 CDD:238103
SPEC 894..1132 CDD:238103
SPEC 1138..1238 CDD:197544
RhoGEF 1287..1457 CDD:238091
PH1_Kalirin_Trio_like 1464..1586 CDD:270060
SH3_Kalirin_1 1652..1711 CDD:212786
SH3-RhoG_link 1708..1892 CDD:406906
RhoGEF 1935..2104 CDD:395496
PH2_Kalirin_Trio_p63RhoGEF 2109..2243 CDD:270061
SH3_Kalirin_2 2327..2385 CDD:212787
Ig strand A 2466..2469 CDD:409353
I-set 2474..2568 CDD:400151
Ig strand A' 2482..2485 CDD:409353
Ig strand B 2491..2498 CDD:409353
Ig strand C 2504..2512 CDD:409353
Ig strand C' 2515..2517 CDD:409353
Ig strand D 2523..2532 CDD:409353
Ig strand E 2534..2538 CDD:409353
Ig strand F 2547..2555 CDD:409353
Ig strand G 2558..2568 CDD:409353
FN3 2572..2663 CDD:238020 13/70 (19%)
STKc_Kalirin_C 2693..2940 CDD:271017 19/104 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.