DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10126 and Efcab6

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_006521594.2	Gene:	Efcab6 / 77627	MGIID:	1924877	Length:	1536	Species:	Mus musculus

Alignment Length:	183	Identity:	36/183 - (19%)
Similarity:	66/183 - (36%)	Gaps:	55/183 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 RAFRAMDDDGSKALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEF------LLKL 122
            |..:..|.|....::..||:..:....||:|.||.:|:...:|...:|.....:|      |||.
Mouse  1365 RECKEKDTDKQGTISAAEFLALVEKFKLDISREESQQLIVKYDLKNNGKFAYCDFIQSCVLLLKA 1429

  Fly   123 RPPMPQSRLNI---------------------------------IDQAFNKMDRDEDGVITIQDL 154
            :......|:.|                                 :.::|...|::..|::::.|.
Mouse  1430 KETSLMRRMRIQNADKMKEAGMETPSFYSALLRIQPKIVHCWRPMRRSFKTYDKNGTGLLSVADF 1494

  Fly   155 KNV---YSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYY 204
            :.|   ||:         ..||:|    |.|..|....:|..||:..:|:..:
Mouse  1495 RKVLRQYSI---------NLSEEE----FFHVLEYYDKSLSSKISYNDFLRAF 1534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	14/60 (23%)
		EFh	64..119	CDD:238008	14/60 (23%)
		EFh	97..154	CDD:238008	13/95 (14%)
		EF-hand_7	98..158	CDD:290234	14/101 (14%)
		EF-hand_7	134..204	CDD:290234	17/72 (24%)
Efcab6	XP_006521594.2	FRQ1	119..285	CDD:227455
		FRQ1	338..501	CDD:227455
		EFh_PEF	787..>952	CDD:355382
		EF-hand motif	787..823	CDD:320054
		EF-hand motif	828..889	CDD:320054
		EF-hand motif	890..922	CDD:320054
		EFh_PI-PLC	894..1004	CDD:333715
		EF-hand motif	894..922	CDD:320029
		EF-hand_7	898..952	CDD:372618
		EF-hand motif	929..954	CDD:320029
		EF-hand_11	1197..1301	CDD:370222
		PTZ00183	1364..1532	CDD:185503	36/179 (20%)
		EF-hand_7	1474..1534	CDD:372618	17/72 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910