DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Capsl

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_083617.2	Gene:	Capsl / 75568	MGIID:	1922818	Length:	208	Species:	Mus musculus

Alignment Length:	202	Identity:	98/202 - (48%)
Similarity:	144/202 - (71%)	Gaps:	3/202 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRD 88
            :..||.|:.::|:..  .|||.:|||.||:||:.||.||||.||.|||:.::.|:.:||:.|:.|
Mouse     8 DREMAIQSKKKLSTA--TDPIERLRLQCLARGSAGIKGLGRVFRIMDDNNNRTLDFKEFLKGLND 70

  Fly    89 TGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQD 153
            ..:.:.:||.:::|..||.||||:|:..||||.|||||.::|..:|.:||.|:|:..||||||:|
Mouse    71 YAVVMEKEEAEELFQRFDRDGSGTIDFNEFLLTLRPPMSRARKEVIMKAFRKLDKTGDGVITIED 135

  Fly   154 LKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDMFFD 218
            |:.||:.|.|||||:||.:|:::...||.||:... :.||.:|.|||:||||.:|||||.|::|.
Mouse   136 LREVYNAKHHPKYQNGEWTEEQVFRKFLDNFDSPY-DKDGLVTPEEFMNYYAGVSASIDTDVYFI 199

  Fly   219 LMMRRAY 225
            :||..|:
Mouse   200 IMMTTAW 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	24/56 (43%)
		EFh	64..119	CDD:238008	22/54 (41%)
		EFh	97..154	CDD:238008	30/56 (54%)
		EF-hand_7	98..158	CDD:290234	31/59 (53%)
		EF-hand_7	134..204	CDD:290234	35/69 (51%)
Capsl	NP_083617.2	EF-hand_7	44..101	CDD:290234	24/56 (43%)
		EFh	46..101	CDD:238008	22/54 (41%)
		EFh	79..138	CDD:238008	32/58 (55%)
		EF-hand_7	80..140	CDD:290234	31/59 (53%)
		EF-hand_7	116..185	CDD:290234	35/69 (51%)
		EFh	116..182	CDD:298682	33/66 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834887
Domainoid	1	1.000	83	1.000	Domainoid score	I8340
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16959
Inparanoid	1	1.050	207	1.000	Inparanoid score	I3696
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56894
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005596
OrthoInspector	1	1.000	-	-		otm42563
orthoMCL	1	0.900	-	-		OOG6_103375
Panther	1	1.100	-	-	LDO	PTHR34524
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5421
SonicParanoid	1	1.000	-	-		X4009
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790