DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Dclk2

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001344389.1	Gene:	Dclk2 / 70762	MGIID:	1918012	Length:	772	Species:	Mus musculus

Alignment Length:	238	Identity:	47/238 - (19%)
Similarity:	87/238 - (36%)	Gaps:	58/238 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LKNPNCDLYTLEANMASQ--ALRELTDGEDK-DPITKLRLLCLSRGATGILGLGRAFRAMDD--- 71
            :|:||..:...|...|:.  .:.||..|.|. |.||.........|:..:..|..|.|.:..
Mouse   462 VKHPNIIMLVEEMETATDLFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLANALRYLHSLSI 526

  Fly    72 ----------------DGSKALNEEEF-----ITG----IRDTGLDVSEEEIKQMFATFDEDGSG 111
                            ||:|:|...:|     :.|    :..|...|:.|.|.:.......|...
Mouse   527 VHRDIKPENLLVCEYPDGTKSLKLGDFGLATVVEGPLYTVCGTPTYVAPEIIAETGYGLKVDVWA 591

  Fly   112 SINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLKNVYSVK---EHPKYQSGEKSE 173
            :..:|..||...||. :|..|:.:..|::                :.:.|   ..|.:.:...|.
Mouse   592 AGVITYILLCGFPPF-RSENNLQEDLFDQ----------------ILAGKLEFPAPYWDNITDSA 639

  Fly   174 DEILTDFLHNFEGGRGNLDGKITREEFVNY-YATISASIDNDM 215
            .|:::..|      :.|::.:.|..|.::: :.:..||.:|:|
Mouse   640 KELISQML------QVNVEARCTAGEILSHPWVSDDASQENNM 676

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	15/84 (18%)
		EFh	64..119	CDD:238008	14/82 (17%)
		EFh	97..154	CDD:238008	10/56 (18%)
		EF-hand_7	98..158	CDD:290234	10/59 (17%)
		EF-hand_7	134..204	CDD:290234	9/73 (12%)
Dclk2	NP_001344389.1	DCX	67..157	CDD:214711
		DCX	191..279	CDD:214711
		PKc_like	407..665	CDD:328722	43/225 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900