DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and dclk2a

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001128593.1	Gene:	dclk2a / 572548	ZFINID:	ZDB-GENE-050420-170	Length:	810	Species:	Danio rerio

Alignment Length:	181	Identity:	31/181 - (17%)
Similarity:	80/181 - (44%)	Gaps:	28/181 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 LLCLSRGATGILGLGRAFRAM--DDDGSKALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSG 111
            |:.|:|..:..:.|.:..|::  .|.|.|..:.::.:.|  ::.:..|.|..:::..|.:.:.:.
Zfish    95 LMELTRSLSDNVNLPQGVRSIYTADGGKKITSLDDLVEG--ESYVCASNEPFRKVDYTKNVNPNW 157

  Fly   112 SINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLKNVYSVKEHPKYQSGEK---SE 173
            |:|:.....:..|.:..::..:.::  ...|..:..::|:  :::....::..:....:|   |.
Zfish   158 SVNVKTGASRSMPSLTATKNELRER--ESKDYIKPKLVTV--IRSGVKPRKAVRILLNKKTAHSF 218

  Fly   174 DEILTDFLHNFEGGRG------NLDGK--ITREEFVNYYATISASIDNDMF 216
            :::|||.....:...|      .|:||  |..::|..         |:|:|
Zfish   219 EQVLTDITDAIKLDSGAVKRLYTLEGKQIICLQDFFG---------DDDVF 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	11/58 (19%)
		EFh	64..119	CDD:238008	10/56 (18%)
		EFh	97..154	CDD:238008	6/56 (11%)
		EF-hand_7	98..158	CDD:290234	6/59 (10%)
		EF-hand_7	134..204	CDD:290234	13/80 (16%)
dclk2a	NP_001128593.1	DCX	59..149	CDD:214711	11/55 (20%)
		DCX	186..274	CDD:214711	16/86 (19%)
		STKc_DCKL2	418..676	CDD:271086
		S_TKc	420..677	CDD:214567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900