DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and capslb

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001017776.2	Gene:	capslb / 550473	ZFINID:	ZDB-GENE-050417-298	Length:	209	Species:	Danio rerio

Alignment Length:	199	Identity:	103/199 - (51%)
Similarity:	140/199 - (70%)	Gaps:	3/199 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 MASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRDTGL 91
            |...|.::|  .|..|||.:|||.|||||..||.||||.||.||||.::.|:.:|||.|:.|.|:
Zfish    11 MMINAKKQL--AECSDPIERLRLQCLSRGCAGIKGLGRTFRIMDDDNNRTLDLKEFIKGLNDYGV 73

  Fly    92 DVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLKN 156
            .:.:||...:|..||.||||.|:..|||:.|||||..:|..::.|||.|:|:..|||||::|||.
Zfish    74 LMEKEEAINLFQQFDRDGSGQIDFDEFLITLRPPMSNARKEVVLQAFKKLDKTGDGVITVEDLKG 138

  Fly   157 VYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDMFFDLMM 221
            ||.|::||||.:||.:||:|...||.:|: ...:.|||:|:|||:|||:.:|||||.|::|.|||
Zfish   139 VYDVRKHPKYLNGEWTEDQIFRKFLDSFD-SPDDKDGKVTKEEFMNYYSGVSASIDTDIYFILMM 202

  Fly   222 RRAY 225
            |.|:
Zfish   203 RNAW 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	27/56 (48%)
		EFh	64..119	CDD:238008	25/54 (46%)
		EFh	97..154	CDD:238008	28/56 (50%)
		EF-hand_7	98..158	CDD:290234	30/59 (51%)
		EF-hand_7	134..204	CDD:290234	36/69 (52%)
capslb	NP_001017776.2	EF-hand_7	44..101	CDD:290234	27/56 (48%)
		EFh	46..101	CDD:238008	25/54 (46%)
		EFh	79..136	CDD:298682	28/56 (50%)
		EF-hand_7	82..140	CDD:290234	30/57 (53%)
		EF-hand_7	118..185	CDD:290234	36/67 (54%)
		EFh	119..182	CDD:298682	33/63 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16959
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3592
OMA	1	1.010	-	-		QHG56894
OrthoDB	1	1.010	-	-		D1377102at2759
OrthoFinder	1	1.000	-	-		FOG0005596
OrthoInspector	1	1.000	-	-		mtm6408
orthoMCL	1	0.900	-	-		OOG6_103375
Panther	1	1.100	-	-	LDO	PTHR34524
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5421
SonicParanoid	1	1.000	-	-		X4009
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800