DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10126 and capsl

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_012817881.1	Gene:	capsl / 549278	XenbaseID:	XB-GENE-962396	Length:	208	Species:	Xenopus tropicalis

Alignment Length:	202	Identity:	103/202 - (50%)
Similarity:	147/202 - (72%)	Gaps:	3/202 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRD 88
            :.:||.||.:.|:  ...||:.||||.|||||:.||.||||.||.|||||:|.|:.:||..|:.|
Frog     8 DRDMALQAKKNLS--SCTDPVEKLRLQCLSRGSAGIKGLGRVFRIMDDDGNKTLDFKEFSKGLSD 70

  Fly    89 TGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQD 153
            .|:.:.:.|.:::|:.||:||||:|:..|||:.|||||..:|.::|.|||.|:|:..|||:||:|
Frog    71 YGVMMDKTETQELFSVFDKDGSGTIDFDEFLVTLRPPMSNARKDMILQAFRKLDKSGDGVVTIED 135

  Fly   154 LKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDMFFD 218
            |:.||:.|.|||||:||.:||::...||.||:... :.||::|.:||:||||.:|||||.|::|.
Frog   136 LRGVYNAKHHPKYQNGEWTEDQVFRSFLDNFDSPY-DKDGQVTPDEFMNYYAGVSASIDTDIYFI 199

  Fly   219 LMMRRAY 225
            .|||.|:
Frog   200 TMMRNAW 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	27/56 (48%)
		EFh	64..119	CDD:238008	25/54 (46%)
		EFh	97..154	CDD:238008	29/56 (52%)
		EF-hand_7	98..158	CDD:290234	30/59 (51%)
		EF-hand_7	134..204	CDD:290234	35/69 (51%)
capsl	XP_012817881.1	EF-hand_7	44..101	CDD:290234	27/56 (48%)
		EFh	46..101	CDD:238008	25/54 (46%)
		EFh	79..136	CDD:238008	29/56 (52%)
		EF-hand_7	81..140	CDD:290234	30/58 (52%)
		EFh	115..182	CDD:298682	33/67 (49%)
		EF-hand_7	116..185	CDD:290234	35/69 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	64	1.000	Domainoid score	I9988
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H16959
Inparanoid	1	1.050	213	1.000	Inparanoid score	I3536
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377102at2759
OrthoFinder	1	1.000	-	-		FOG0005596
OrthoInspector	1	1.000	-	-		mtm9381
Panther	1	1.100	-	-	LDO	PTHR34524
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5421
SonicParanoid	1	1.000	-	-		X4009
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.190