DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10126 and Unc-89

DIOPT Version :9

Sequence 1:NP_788664.2 Gene:CG10126 / 41579 FlyBaseID:FBgn0038088 Length:227 Species:Drosophila melanogaster
Sequence 2:NP_001097440.1 Gene:Unc-89 / 3346201 FlyBaseID:FBgn0053519 Length:4218 Species:Drosophila melanogaster


Alignment Length:232 Identity:50/232 - (21%)
Similarity:94/232 - (40%) Gaps:42/232 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 KGWSLKNPNCDLYTLEANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDG 73
            :||    ...|:......|:|...:|..|.|    ..||.:|             |.....:::.
  Fly    58 EGW----VPIDILEFNPTMSSSNGKESGDAE----FRKLTIL-------------RELVETEEEF 101

  Fly    74 SKALNE--EEFITGIRDTGLDVSEEEIKQ-MFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIID 135
            |:.|..  |::|.||....:..|..:.|. :|..|.:......|:.:..||.....|    |::.
  Fly   102 SRDLLHVVEKYIKGIDKPVVPRSVRDNKDIIFCNFLQIAEFHNNVLKEGLKCYSNQP----NMVA 162

  Fly   136 QAFNKMDRDEDGVIT-------IQD-LKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLD 192
            :.|.:::||.|..:.       .|| |.:....|::.:..|.:..:|:.|.:.| .....|.| |
  Fly   163 KTFLRLERDFDKHVVYCQNEPLAQDYLGSSPDAKKYFQELSKQLGDDKSLAEHL-KLPIQRIN-D 225

  Fly   193 GKITREEFVNYYATISASI-DNDMFFDLMM---RRAY 225
            .::..::|:.|..::..:: |.:...:||:   .|||
  Fly   226 YQLLFKDFIKYSLSLKENVKDLERALELMLSVPSRAY 262

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10126NP_788664.2 EF-hand_7 62..119 CDD:290234 12/59 (20%)
EFh 64..119 CDD:238008 12/57 (21%)
EFh 97..154 CDD:238008 14/65 (22%)
EF-hand_7 98..158 CDD:290234 15/68 (22%)
EF-hand_7 134..204 CDD:290234 16/77 (21%)
Unc-89NP_001097440.1 RhoGEF 90..260 CDD:238091 37/188 (20%)
PH_unc89 275..388 CDD:270134
Atrophin-1 <493..690 CDD:331285
TonB_N 502..>596 CDD:318287
I-set 1017..1108 CDD:333254
I-set 1123..1212 CDD:254352
I-set <1236..1299 CDD:333254
I-set 1313..1403 CDD:254352
Ig_3 1406..1487 CDD:316449
I-set 1499..1595 CDD:254352
I-set 1599..1690 CDD:333254
I-set 1694..1786 CDD:254352
I-set <1836..1903 CDD:333254
I-set 1922..2005 CDD:333254
I-set 2018..2108 CDD:333254
I-set 2113..2214 CDD:333254
I-set 2220..2302 CDD:254352
I-set 2318..2408 CDD:254352
I-set 2415..2506 CDD:254352
I-set 2519..2608 CDD:254352
I-set 2615..2696 CDD:254352
I-set 2717..2805 CDD:254352
FN3 2834..2925 CDD:238020
I-set <2996..3063 CDD:333254
I-set 3067..3157 CDD:333254
PK_Unc-89_rpt1 3182..3440 CDD:271011
I-set 3654..3744 CDD:333254
FN3 3748..3840 CDD:238020
STKc_Unc-89_rpt2 3893..4151 CDD:271014
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0032
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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