DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Efcab6

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_038936237.1	Gene:	Efcab6 / 315179	RGDID:	1309065	Length:	1509	Species:	Rattus norvegicus

Alignment Length:	177	Identity:	35/177 - (19%)
Similarity:	62/177 - (35%)	Gaps:	55/177 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 DDDGSKALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEF------LLKLRPPMPQ 128
            |.|...::...||:..|....||:|.||.:|:...:|...:|.....:|      |||.:.....
  Rat  1344 DTDKQGSITAAEFLALIEKFKLDISREESQQLLVKYDMKNNGKFAYCDFIQSCVLLLKAKETSLM 1408

  Fly   129 SRLNI---------------------------------IDQAFNKMDRDEDGVITIQDLKNV--- 157
            .|:.|                                 :.:.|...|.:..|::::.|.:.|
  Rat  1409 RRMRIQNADKMKEAGVETPSFYSALLRIQPKIVHCWRPMRRTFKTYDENGTGLLSVADFRKVLRQ 1473

  Fly   158 YSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYY 204
            :|:         ..||:|    |.|..|....:|..||:..:|:..:
  Rat  1474 FSI---------NLSEEE----FFHVLEYYDKSLSSKISYNDFLRAF 1507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	14/54 (26%)
		EFh	64..119	CDD:238008	14/54 (26%)
		EFh	97..154	CDD:238008	13/95 (14%)
		EF-hand_7	98..158	CDD:290234	14/101 (14%)
		EF-hand_7	134..204	CDD:290234	16/72 (22%)
Efcab6	XP_038936237.1	FRQ1	82..264	CDD:227455
		EFh_parvalbumin_like	<420..490	CDD:330177
		EF-hand motif	429..457	CDD:319994
		EF-hand motif	465..490	CDD:319994
		EFh_PI-PLC	869..980	CDD:333715
		EF-hand motif	869..897	CDD:320029
		EF-hand_7	873..927	CDD:404394
		EF-hand motif	904..929	CDD:320029
		FRQ1	1086..1247	CDD:227455
		EF-hand_11	1170..1274	CDD:401068
		PTZ00183	1335..1505	CDD:185503	35/173 (20%)
		EF-hand_7	1447..1507	CDD:404394	16/72 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910