DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Dapk1

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_008769663.1	Gene:	Dapk1 / 306722	RGDID:	1311629	Length:	1442	Species:	Rattus norvegicus

Alignment Length:	138	Identity:	28/138 - (20%)
Similarity:	41/138 - (29%)	Gaps:	57/138 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LRLLCLSRGATGILGLGRAFRAMDDDGSKA-----LNEEEFITGI-----RDT--GLDVSEEEIK 99
            :|.|||         :|....|:..||..|     ..:.|.:.|:     :||  ||.:.:....
  Rat   626 VRYLCL---------MGANVEALTLDGKTAEDLAKAEQHEHVAGLLARLRKDTHRGLFIQQLRPT 681

  Fly   100 Q------MFATFDEDGSG-------------------------SINMTEFLLKLRPPMPQSRLNI 133
            |      ....|...|||                         |.|.|.|     ||.|.:....
  Rat   682 QNLQPRIKLKLFGHSGSGKSTLVESLKCGLLRSFFRRRRPRLSSTNSTRF-----PPSPLATKPT 741

  Fly   134 IDQAFNKM 141
            :..:.|.:
  Rat   742 VSVSINNL 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	19/99 (19%)
		EFh	64..119	CDD:238008	18/97 (19%)
		EFh	97..154	CDD:238008	13/76 (17%)
		EF-hand_7	98..158	CDD:290234	13/75 (17%)
		EF-hand_7	134..204	CDD:290234	1/8 (13%)
Dapk1	XP_008769663.1	STKc_DAPK1	7..275	CDD:271096
		S_TKc	13..275	CDD:214567
		Ank_2	<337..409	CDD:289560
		ANK	373..497	CDD:238125
		ANK repeat	378..409	CDD:293786
		Ank_2	383..475	CDD:289560
		ANK repeat	412..442	CDD:293786
		ANK	439..564	CDD:238125
		ANK repeat	444..475	CDD:293786
		Ank_2	449..541	CDD:289560
		ANK repeat	477..508	CDD:293786
		ANK	505..629	CDD:238125	1/2 (50%)
		ANK repeat	510..541	CDD:293786
		ANK repeat	543..574	CDD:293786
		Ank_2	548..638	CDD:289560	5/20 (25%)
		ANK repeat	576..607	CDD:293786
		ANK repeat	609..638	CDD:293786	5/20 (25%)
		Death_DAPK1	1308..1393	CDD:260052
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900