DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Mylk3

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_001104280.1	Gene:	Mylk3 / 291926	RGDID:	1305801	Length:	786	Species:	Rattus norvegicus

Alignment Length:	148	Identity:	25/148 - (16%)
Similarity:	59/148 - (39%)	Gaps:	36/148 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 AFRAMDDDGSKALNEEEFITGIRD----TGLDVSEEEI------KQMFATFDEDGSGSINMTEFL 119
            |...:||..:.....|..:..|:|    |...||:.|:      .|:....:.  |..:.:...:
  Rat   450 AIVVLDDSAAPPAPFEHRVVSIKDTLISTSYTVSQHEVLGGGRFGQVHRCTER--STGLALAAKI 512

  Fly   120 LKLRPPMPQSRLNIIDQAFNKMDRDE--DGVITIQDLKNVYSVKEHPKYQSGEKSEDEILTDFLH 182
            :|::               |..||::  :.:..:..|.:|..::.:..::|  |:...::.:::.
  Rat   513 IKVK---------------NIKDREDVKNEINIMNQLSHVNLIQLYDAFES--KNSFTLIMEYVD 560

  Fly   183 NFEGGRGNLDGKITREEF 200
            .     |.|..:||.|::
  Rat   561 G-----GELFDRITDEKY 573

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	12/63 (19%)
		EFh	64..119	CDD:238008	12/63 (19%)
		EFh	97..154	CDD:238008	7/64 (11%)
		EF-hand_7	98..158	CDD:290234	7/67 (10%)
		EF-hand_7	134..204	CDD:290234	12/69 (17%)
Mylk3	NP_001104280.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	233..258
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	279..315
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	333..443
		STKc_MLCK3	477..737	CDD:271094	19/121 (16%)
		S_TKc	485..737	CDD:214567	16/113 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900