DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and mek1

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_594908.1	Gene:	mek1 / 2541604	PomBaseID:	SPAC14C4.03	Length:	445	Species:	Schizosaccharomyces pombe

Alignment Length:	151	Identity:	36/151 - (23%)
Similarity:	55/151 - (36%)	Gaps:	41/151 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GILGLGRAFRAMDDD---------------GSKALNEEEFITGIRDTGLD-------VSEEEIKQ 100
            ||.|..|.:.|||::               .:|...|:..:|.:|.  ||       ..|...:.
pombe   167 GIGGFSRIYMAMDNNTGGQYACKIIDKKKISTKRFFEDHEMTILRK--LDHPNIIKVNMEYNSET 229

  Fly   101 MFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQDLK--NVYSVKEH 163
            .|..|:|..:|. ::..:|.||......:.|.|:.|....:....:..|..:|||  |:...
pombe   230 QFFIFEEMVTGG-DLFSYLTKLGTVPEVTTLFIMFQILQGLKYLHEQNIIHRDLKLENILIA--- 290

  Fly   164 PKYQSGEKSEDE----ILTDF 180
                   .|.|.    |||||
pombe   291 -------SSSDTIFRIILTDF 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	15/78 (19%)
		EFh	64..119	CDD:238008	15/76 (20%)
		EFh	97..154	CDD:238008	11/56 (20%)
		EF-hand_7	98..158	CDD:290234	15/61 (25%)
		EF-hand_7	134..204	CDD:290234	13/53 (25%)
mek1	NP_594908.1	FHA	39..141	CDD:238017
		STKc_CAMK	163..420	CDD:270687	36/151 (24%)
		S_TKc	164..421	CDD:214567	36/151 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900