DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10126 and Camk4

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_036859.2	Gene:	Camk4 / 25050	RGDID:	2264	Length:	474	Species:	Rattus norvegicus

Alignment Length:	155	Identity:	41/155 - (26%)
Similarity:	65/155 - (41%)	Gaps:	49/155 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EANMASQALRELTDGEDK-DPI-TKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGI 86
            |:|.||...:...||:|| ||: .|::           .|...|.:|..|:..|..:||
  Rat   347 ESNKASSEAQPAQDGKDKTDPLENKMQ-----------AGDHEAAKAAADETMKLQSEE------ 394

  Fly    87 RDTGLDVSEEE-IKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVIT 150
                  |.||| :|:.....:|:...|        ::.|..|:.||...||   :|.|:.:
  Rat   395 ------VEEEEGVKEEEEEEEEEEETS--------RMVPQEPEDRLETDDQ---EMKRNSE---- 438

  Fly   151 IQDLKNVYSVKEHPKYQSGEKSEDE 175
             :.||   ||:|    :...|:|:|
  Rat   439 -ETLK---SVEE----EMDPKAEEE 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	13/57 (23%)
		EFh	64..119	CDD:238008	13/55 (24%)
		EFh	97..154	CDD:238008	12/57 (21%)
		EF-hand_7	98..158	CDD:290234	13/59 (22%)
		EF-hand_7	134..204	CDD:290234	12/42 (29%)
Camk4	NP_036859.2	STKc_CaMKIV	38..331	CDD:270987
		Autoinhibitory domain	297..336
		PP2A-binding. /evidence=ECO:0000250	302..319
		Calmodulin-binding. /evidence=ECO:0000255	318..337
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..474		41/155 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900