DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Camkv

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_663596.1	Gene:	Camkv / 235604	MGIID:	2384296	Length:	512	Species:	Mus musculus

Alignment Length:	180	Identity:	37/180 - (20%)
Similarity:	62/180 - (34%)	Gaps:	49/180 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDD--------------DGSKALNEEEFIT 84
            |:||..|...:.|....|            ..|||.|.              ||.|.....:...
Mouse    19 EVTDRYDLGQVIKTEEFC------------EIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEI 71

  Fly    85 GIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLN-IIDQAFNKMDRDEDGV 148
            ||...   |....|.|:...|       :...|:.:.|.....:...: |:||.:.. :||...|
Mouse    72 GILKM---VKHPNILQLVDVF-------VTRKEYFIFLELATGREVFDWILDQGYYS-ERDTSNV 125

  Fly   149 I--TIQDLKNVYSVK--------EHPKYQSGEKSEDEILTDF-LHNFEGG 187
            :  .::.:..::|:|        |:..|.:..|:...:::|| |...|.|
Mouse   126 VRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	14/70 (20%)
		EFh	64..119	CDD:238008	14/68 (21%)
		EFh	97..154	CDD:238008	11/59 (19%)
		EF-hand_7	98..158	CDD:290234	11/62 (18%)
		EF-hand_7	134..204	CDD:290234	15/65 (23%)
Camkv	NP_663596.1	STKc_CaMK_like	22..286	CDD:270990	35/177 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	328..347
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	393..512
		DUF5585	397..>511	CDD:375359
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900