DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and zyg-8

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_499571.2	Gene:	zyg-8 / 176639	WormBaseID:	WBGene00006993	Length:	802	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	56/274 - (20%)
Similarity:	96/274 - (35%)	Gaps:	92/274 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 PNCDLYTLEANMASQALRELTDG-------EDKDPITKLRLLCLSRGATGILGLGRAFR------ 67
            ||....|.||:|.|......|:|       |.:|.:::::..| ..|.:|...|.:|.|
Worm   155 PNSGTNTAEASMTSSVCAMETEGTNGDELAESRDMVSEMQRRC-RIGPSGYPHLLKAKRLRFYRN 218

  Fly    68 ----------AMDDDGSKA---LNEEEFITGIRD-TGLDVSEEEIKQMFATFD-----------E 107
                      |:..|..|:   |.|:...|.|.| |.|   ...|:.:| |.|           |
Worm   219 GDQYFKGIQYALQSDRVKSMQPLMEDLMKTVICDSTAL---PHGIRHIF-TIDGAQRITSVDQFE 279

  Fly   108 DGSGSINMTEFLLKLRPPMPQSR------------------------LNIIDQAFNKMDRDEDGV 148
            ||.|.:..:....|   |:..||                        |::::......|.....:
Worm   280 DGGGYVCSSTDAFK---PVDYSRAAEPSWRLTLANRYNRHLETKKLALSVVEPCHENTDFVFPRI 341

  Fly   149 ITIQDLKNVYS---VKEHPKYQSGEKSEDEILTD--FLHNFEGGR----GNLDGK--ITREEFVN 202
            |.:  ::|...   :..|...:...:|.|::|.|  |:...:.|.    ..|.|:  ::.::|..
Worm   342 IKV--IRNGVKPRRISRHLLNKKTARSFDQVLRDLTFVVKLDSGAIRKLFTLSGRPVLSLQDFFR 404

  Fly   203 YYATISASIDNDMF 216
                     |:|:|
Worm   405 ---------DDDVF 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	21/87 (24%)
		EFh	64..119	CDD:238008	20/85 (24%)
		EFh	97..154	CDD:238008	15/91 (16%)
		EF-hand_7	98..158	CDD:290234	16/94 (17%)
		EF-hand_7	134..204	CDD:290234	13/80 (16%)
zyg-8	NP_499571.2	DCX	206..298	CDD:214711	23/98 (23%)
		DCX	335..423	CDD:214711	16/86 (19%)
		STKc_DCKL	481..742	CDD:270997
		S_TKc	482..743	CDD:214567
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900