DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and AgaP_AGAP007666

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_308204.3	Gene:	AgaP_AGAP007666 / 1269561	VectorBaseID:	AGAP007666	Length:	215	Species:	Anopheles gambiae

Alignment Length:	202	Identity:	125/202 - (61%)
Similarity:	158/202 - (78%)	Gaps:	1/202 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRD 88
            |:.|.:::.|.|:.|...|.|.|||.:||:|||:|||||||.||.|||||:|.||.||||.|:.|
Mosquito    13 ESEMINRSRRALSSGALTDSIEKLRHMCLARGASGILGLGRCFRRMDDDGNKQLNLEEFIKGLHD 77

  Fly    89 TGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVITIQD 153
            ||||:|.||..:||..||.||||||||||||:.:||.|.:||::|:.|||.|:|:..||.|||:|
Mosquito    78 TGLDISAEEATEMFNKFDTDGSGSINMTEFLVAIRPNMSESRVSIVKQAFAKLDKTGDGTITIED 142

  Fly   154 LKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDMFFD 218
            ||||||||.||.|.|||::||.||..:|.||| ..||:||.:|:|||:||||.:|||||:|.:||
Mosquito   143 LKNVYSVKNHPLYISGEETEDVILRKYLANFE-ENGNVDGSVTKEEFLNYYAGLSASIDSDAYFD 206

  Fly   219 LMMRRAY 225
            ||||:|:
Mosquito   207 LMMRQAF 213

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	40/56 (71%)
		EFh	64..119	CDD:238008	38/54 (70%)
		EFh	97..154	CDD:238008	33/56 (59%)
		EF-hand_7	98..158	CDD:290234	36/59 (61%)
		EF-hand_7	134..204	CDD:290234	42/69 (61%)
AgaP_AGAP007666	XP_308204.3	EF-hand_7	51..108	CDD:290234	40/56 (71%)
		EFh	55..112	CDD:238008	39/56 (70%)
		EFh	86..143	CDD:238008	33/56 (59%)
		EF-hand_7	89..147	CDD:290234	36/57 (63%)
		EF-hand_7	123..192	CDD:290234	42/69 (61%)
		EFh	123..189	CDD:298682	40/66 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I14075
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16959
Inparanoid	1	1.050	252	1.000	Inparanoid score	I5583
OMA	1	1.010	-	-		QHG56894
OrthoDB	1	1.010	-	-		D1377102at2759
OrthoFinder	1	1.000	-	-		FOG0005596
OrthoInspector	1	1.000	-	-		otm49717
Panther	1	1.100	-	-	LDO	PTHR34524
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4009
TreeFam	1	0.960	-	-
	13	12.940