DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Speg

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	XP_011236945.1	Gene:	Speg / 11790	MGIID:	109282	Length:	3272	Species:	Mus musculus

Alignment Length:	174	Identity:	36/174 - (20%)
Similarity:	67/174 - (38%)	Gaps:	42/174 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LSRGATGILGLGRAFRAMDDDGSKALNEEEFITGIRDTGLDVSEEEIKQMFATFDEDGSGSINMT 116
            ||..:..:..|||:.|.: ..||:.|::.:|.            ||.::.....|...:
Mouse   391 LSEASGRLSALGRSPRLV-RAGSRILDKLQFF------------EERRRSLERSDSPPA------ 436

  Fly   117 EFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGV------ITIQDLKNVY-SVKEHPK-YQSGEKSE 173
                .|||.:|..:...::|     .:.|.|.      .:.::|::.. ||.|..: :|....|.
Mouse   437 ----PLRPWVPLRKARSLEQ-----PKSEGGAAWGTPEASQEELRSPRGSVAERRRLFQQKAASL 492

  Fly   174 DE------ILTDFLHNFEGGRGNLDGKITREEFVNYYATISASI 211
            ||      ..:|....|....|.:....:|||.|..:.::.|::
Mouse   493 DERTRQRSATSDLELRFAQELGRIRRSTSREELVRSHESLRATL 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	11/56 (20%)
		EFh	64..119	CDD:238008	9/54 (17%)
		EFh	97..154	CDD:238008	9/62 (15%)
		EF-hand_7	98..158	CDD:290234	9/65 (14%)
		EF-hand_7	134..204	CDD:290234	18/83 (22%)
Speg	XP_011236945.1	I-set	45..127	CDD:369462
		PHA03247	<320..697	CDD:223021	36/174 (21%)
		I-set	737..826	CDD:369462
		SPEG_u2	827..883	CDD:293256
		I-set	884..974	CDD:369462
		Ig	988..1073	CDD:386229
		I-set	1079..1168	CDD:369462
		I-set	1203..1292	CDD:369462
		FN3	1297..>1374	CDD:238020
		I-set	1500..1589	CDD:369462
		STKc_SPEG_rpt1	1613..1869	CDD:271010
		PHA03247	<1951..2355	CDD:223021
		PHA03307	2235..>2557	CDD:223039
		I-set	2597..2687	CDD:369462
		FN3	2691..2777	CDD:238020
		PHA03247	<2760..2981	CDD:223021
		STKc_SPEG_rpt2	2967..3223	CDD:271013
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900