DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10126 and Mylk2

DIOPT Version :9

Sequence 1:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster
Sequence 2:	NP_476557.2	Gene:	Mylk2 / 117558	RGDID:	620934	Length:	610	Species:	Rattus norvegicus

Alignment Length:	153	Identity:	33/153 - (21%)
Similarity:	50/153 - (32%)	Gaps:	58/153 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 FITGIRDTGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKL------RPPMPQSRLNI------- 133
            |:..:|...||:..|.|.            .:|.|..|:|:      |...|..:|.:
  Rat   410 FMHKMRVLHLDLKPENIL------------CVNTTGHLVKIIDFGLARRYNPNEKLKVNFGTPEF 462

  Fly   134 -------IDQAFNKMDRDEDGVIT---------------IQDLKNVYSVKEHPKYQSGEKSEDEI 176
                   .||..:|.|....||||               .:.|.||.|...:...::.|...||
  Rat   463 LSPEVVNYDQISDKTDMWSLGVITYMLLSGLSPFLGDDDTETLNNVLSANWYFDEETFEAVSDE- 526

  Fly   177 LTDFLHNFEGGRGNLDGKITREE 199
            ..||:.|.          ||:::
  Rat   527 AKDFVSNL----------ITKDQ 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	8/36 (22%)
		EFh	64..119	CDD:238008	8/36 (22%)
		EFh	97..154	CDD:238008	16/91 (18%)
		EF-hand_7	98..158	CDD:290234	18/94 (19%)
		EF-hand_7	134..204	CDD:290234	20/81 (25%)
Mylk2	NP_476557.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..168
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	196..240
		PKc_like	295..554	CDD:419665	33/153 (22%)
		Calmodulin-binding. /evidence=ECO:0000250	588..600
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900