DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG31345 and CG10126

DIOPT Version :9

Sequence 1:	NP_731744.1	Gene:	CG31345 / 41576	FlyBaseID:	FBgn0051345	Length:	213	Species:	Drosophila melanogaster
Sequence 2:	NP_788664.2	Gene:	CG10126 / 41579	FlyBaseID:	FBgn0038088	Length:	227	Species:	Drosophila melanogaster

Alignment Length:	205	Identity:	136/205 - (66%)
Similarity:	167/205 - (81%)	Gaps:	0/205 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 YSKEAELKNLAKRELANGLDKDPIYKLRLQCFSRGATGILGLSRSFRVMDDDGSKSLSPEEFKKG 71
            |:.||.:.:.|.|||.:|.|||||.||||.|.||||||||||.|:||.|||||||:|:.|||..|
  Fly    21 YTLEANMASQALRELTDGEDKDPITKLRLLCLSRGATGILGLGRAFRAMDDDGSKALNEEEFITG 85

  Fly    72 VTDIGLDLTDSEIDEMFSRFDTDGSGNINMTEFLVKLRPPMNNSRISIIEKAFDKMDANGDGQIT 136
            :.|.|||:::.||.:||:.||.||||:|||||||:||||||..||::||::||:|||.:.||.||
  Fly    86 IRDTGLDVSEEEIKQMFATFDEDGSGSINMTEFLLKLRPPMPQSRLNIIDQAFNKMDRDEDGVIT 150

  Fly   137 VTDLKNVYSVRDHPKYLSGEMTENQIFTQFLKNFEVGAPNPDGIVTREEFINYYATISASIDNDA 201
            :.||||||||::||||.|||.:|::|.|.||.|||.|..|.||.:|||||:|||||||||||||.
  Fly   151 IQDLKNVYSVKEHPKYQSGEKSEDEILTDFLHNFEGGRGNLDGKITREEFVNYYATISASIDNDM 215

  Fly   202 YFDLMMRQAY 211
            :||||||:||
  Fly   216 FFDLMMRRAY 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG31345	NP_731744.1	EF-hand_7	48..105	CDD:290234	35/56 (63%)
		EFh	48..105	CDD:238008	35/56 (63%)
		EFh	83..136	CDD:238008	34/52 (65%)
		EF-hand_7	84..144	CDD:290234	39/59 (66%)
		EF-hand_7	120..190	CDD:290234	43/69 (62%)
		EFh	120..187	CDD:298682	41/66 (62%)
CG10126	NP_788664.2	EF-hand_7	62..119	CDD:290234	35/56 (63%)
		EFh	64..119	CDD:238008	34/54 (63%)
		EFh	97..154	CDD:238008	36/56 (64%)
		EF-hand_7	98..158	CDD:290234	39/59 (66%)
		EF-hand_7	134..204	CDD:290234	43/69 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445128
Domainoid	1	1.000	80	1.000	Domainoid score	I8536
eggNOG	1	0.900	-	-		E1_KOG0032
Homologene	1	1.000	-	-		H16959
Inparanoid	1	1.050	215	1.000	Inparanoid score	I3592
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG56894
OrthoDB	1	1.010	-	-		D1377102at2759
OrthoFinder	1	1.000	-	-		FOG0005596
OrthoInspector	1	1.000	-	-		mtm6408
orthoMCL	1	0.900	-	-		OOG6_103375
Panther	1	1.100	-	-	P	PTHR34524
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5421
SonicParanoid	1	1.000	-	-		X4009
	14	13.840