Protein Alignment Ugt37A3 and Ugt1a6a

DIOPT Version :9

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_659545.2
• Gene: Ugt1a6a / 94284
• MGIID: 2137698
• Length: 531
• Species: Mus musculus
• Alignment Length: 554
• Identity: 153/554 - (27%)
• Similarity: 253/554 - (45%)
• Gaps: 92/554 - (16%)

  Fly    25 ANILG---LFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVN-------HKNITVIQVPLS 79
            |::||   |......||.:......:.|:|.||:   :.||.|.||       :....:..|..|
Mouse    22 ASVLGDKLLVVPQDGSHWLSMKEIVEHLSERGHD---IMVLVPEVNLLLGESKYYRRKIFSVTYS 83

  Fly    80 KEEAQQMSDTIGAMSKNDNSNMALSLL------RMSDQMDFMIRKNAETLMNDRVRDLYLNRGNK 138
            .||.|....|.|    |::.....||:      |.:..:..|...|.::|:.|.....:| |.||
Mouse    84 LEELQTRFRTFG----NNHFLPGASLMGPLREYRNNMIVVDMFFSNCQSLLKDSATLSFL-RENK 143

  Fly   139 FDLVIS------GYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISNP---A 194
            ||.:.:      |..:.::       :|.|.:.|....|..|.:.|..:|..|||.    |   .
Mouse   144 FDALFTDPAMPCGVILAEY-------LNLPSVYLFRGFPCSLEHMLGQSPSPVSYV----PRFYT 197

  Fly   195 EGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWY-----KEVYGND--------PKMPEYSEM 246
            :.|..:||.:||::::.::          ..|..:|     .|:..:|        |.:.:.|..
Mouse   198 KFSDHMTFPQRLANFIVNI----------LENYLYYCLYSKYEIIASDLLKRDVSLPSLHQNSLW 252

  Fly   247 LKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNAT--DGAILLSLGS 309
            |.....||       |.| ||.:|:.|.:|||..| |...|.|....:: ||:  .|.::.||||
Mouse   253 LLRYDFVF-------EYP-RPVMPNMIFLGGINCK-KKGKLTQEFEAYV-NASGEHGIVVFSLGS 307

  Fly   310 NVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHPNIKLFI 373
            .|  ..:......::...|.::.:.|:|::..  ..|...| |.:..|||||:|:|.||..:.||
Mouse   308 MV--SEIPEKKAMEIAEALGRIPQTVLWRYTG--TRPSNLAKNTILVKWLPQNDLLGHPKTRAFI 368

  Fly   374 NHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQ 438
            .|:|..||.|...:|.||:.:|:|.||..||..|...|.|:||::|.:.....:.|:..:::|..
Mouse   369 THSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKS 433

  Fly   439 YAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVH-MSFIAANNIDIC-FLIFVI 501
            |.|.:...|:|::|||:...:..::|.|||:||.||.||: |..| :::...:::|:. ||:.::
Mouse   434 YKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLR-PAAHDLTWYQYHSLDVIGFLLAIV 497

  Fly   502 LVSVLVLIKFLVQFIYRRF-----ISKPKKEKTH 530
            |..|.::.|.......:.|     :.|..|.|||
Mouse   498 LTVVFIVFKCCAYGCRKCFGGKGRVKKSHKSKTH 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	141/506 (28%)
		UDPGT	37..526	CDD:278624	145/533 (27%)
Ugt1a6a	NP_659545.2	egt	15..503	CDD:223071	146/524 (28%)
		UDPGT	27..522	CDD:278624	145/538 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840719
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840