Protein Alignment Ugt37A3 and Ugt2a1

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_444414.2
• Gene: Ugt2a1 / 94215
• MGIID: 2149905
• Length: 528
• Species: Mus musculus
• Alignment Length: 555
• Identity: 136/555 - (24%)
• Similarity: 262/555 - (47%)
• Gaps: 61/555 - (10%)

  Fly     5 VEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTV-----LKP 64
            ::..||.::.| :::|.|.|.|:| ::| :..||.:........|....|||||:..     :.|
Mouse     2 LKNILLCSLQI-SLLGMSLGGNVL-IWP-MEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITP 63

  Fly    65 VVNHKNIT--VIQVPLSKEEAQQ-MSDTIGAMSKNDNSNMAL-----SLLRMSDQMDFMIR---- 117
            .....::|  :..||..||:.:. :.|.:....:|..|...:     .:.::.::...:.|
Mouse    64 SSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICD 128

  Fly   118 ---KNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLG--FARKVNAPVIVLATMPPNHLLNP 177
               || |.||:...::       ||::::|...   |..|  .|.|:..|.|......|...:..
Mouse   129 GVLKN-EKLMSKLQKE-------KFEVLLSDPV---FPCGDIVALKLGIPFIYSLRFSPASTVEK 182

  Fly   178 LIGN-PLEVSYAGISNPA---EGSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNW---YKEVYG 235
            ..|. |...||.    ||   |.:..::|..|:.::   :.:.:..::.|...:.|   |.:..|
Mouse   183 HCGKVPFPPSYV----PAILSELTDQMSFTDRVRNF---ISYRMQDYMFETLWKQWDSYYTKALG 240

  Fly   236 NDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD 300
            ....:   .|.:....:....::...|.| ||.:|:...:||:..| ...|||:.:.||:..:.:
Mouse   241 RPTTL---CETMGKAEIWLMRTYWDFEFP-RPYLPNFEFVGGLHCK-PAKPLPKEMEEFVQTSGE 300

  Fly   301 -GAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWEDQ-ENTPGKSANILYSKWLPQDDI 363
             |.::.||||.|  |:|..:....:.:.|:::.::|:|:::.: .:|.|.:..:.  .|:||:|:
Mouse   301 HGIVVFSLGSMV--KNLTDEKANLIASALAQIPQKVLWRYKGKIPDTLGSNTRLF--DWIPQNDL 361

  Fly   364 LAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQE 428
            |.||..:.||.|.|..||.|:.|||.||:.:|:|||||.|...|...|..:.:::.|:.......
Mouse   362 LGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVNMNTMTSSDLLN 426

  Fly   429 AILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNID 493
            |:..:::.|.|.|.....|.::.|:|:...:..::|.|:|:||.||.||:.....:|:...:::|
Mouse   427 ALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWFQYHSLD 491

  Fly   494 ICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            :...:...:.|.::|:.....||:::.....||:|
Mouse   492 VIGFLLACVASAILLVAKCCLFIFQKVGKTGKKKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	112/469 (24%)
Ugt2a1	NP_444414.2	UDPGT	21..516	CDD:278624	127/523 (24%)