Protein Alignment Ugt37A3 and ATG26

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_013290.1
• Gene: ATG26 / 850886
• SGDID: S000004179
• Length: 1198
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 93/496 - (18%)
• Similarity: 161/496 - (32%)
• Gaps: 154/496 - (31%)

  Fly    43 MSAAKVLAENGHNVTVVT--VLKPVVNHKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSL 105
            ::..|.|.:.||.|.::|  ..:..|....|..      :|.|....:.:..|.:|::.|  :.:
Yeast   757 IALGKGLIKEGHQVVIITHSEFRDFVESHGIQF------EEIAGNPVELMSLMVENESMN--VKM 813

  Fly   106 LRMSDQ-----MDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISG-------YFMNDFQLGFARK 158
            ||.:..     :|.:::.:.|.          .|| .|||::|..       :.....|:.:.|.
Yeast   814 LREASSKFRGWIDALLQTSWEV----------CNR-RKFDILIESPSAMVGIHITEALQIPYFRA 867

  Fly   159 VNAPVIVLATMPP-------------NHLLNPLIGNPLEVSYAGISNPAEGSKAVTFQRRLSSYM 210
            ...|.......|.             |:|.:.|..|   |.:.|||......:           :
Yeast   868 FTMPWTRTRAYPHAFIVPDQKRGGNYNYLTHVLFEN---VFWKGISGQVNKWR-----------V 918

  Fly   211 QSLGFGVFSHLSERRNR-----NWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVP 270
            ::||.|..:....::|.     |....::   |...::||.::.|...|....:..
Yeast   919 ETLGLGKTNLFLLQQNNVPFLYNVSPTIF---PPSIDFSEWVRVTGYWFLDDKSTF--------- 971

  Fly   271 SAIEIGGIQIKDKPDPLPQNIAEFLGNATD----------GAILLSLGSNVQGKHLNPDTVAKMF 325
                        ||   |..:.||:..|..          |:|::|....:....:.....|.::
Yeast   972 ------------KP---PAELQEFISEARSKGKKLVYIGFGSIVVSNAKEMTEALVEAVMEADVY 1021

  Fly   326 NVLSKLKERVIWKWEDQENTPGKSA---------NILYSKWLPQDDILAHPNIKLFINHAGKGGI 381
            .:|:|       .|  .|....|:|         |||....:|.|.:.  |.:...::|.|.|..
Yeast  1022 CILNK-------GW--SERLGDKAAKKTEVDLPRNILNIGNVPHDWLF--PQVDAAVHHGGSGTT 1075

  Fly   382 TESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLE------------------------ 422
            ..|...|.|.:..|.|.||...|..:...|.|:.|..|..:
Yeast  1076 GASLRAGLPTVIKPFFGDQFFYAGRVEDIGVGIALKKLNAQTLADALKVATTNKIMKDRAGLIKK 1140

  Fly   423 ----EKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARE 459
                |...:.||..|.:..:||..|    ||.|.:....:|
Yeast  1141 KISKEDGIKTAISAIYNELEYARSV----TLSRVKTPRKKE 1177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	93/496 (19%)
ATG26	NP_013290.1	GRAM	194..>239	CDD:214725
		PH-GRAM1_AGT26	219..335	CDD:275402
		PH-GRAM2_AGT26	581..673	CDD:275403
		GT1_Gtf-like	744..1155	CDD:340817	85/468 (18%)