DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A3 and UGT85A4

DIOPT Version :9

Sequence 1:	NP_650229.2	Gene:	Ugt37A3 / 41574	FlyBaseID:	FBgn0038083	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_177950.1	Gene:	UGT85A4 / 844162	AraportID:	AT1G78270	Length:	489	Species:	Arabidopsis thaliana

Alignment Length:	541	Identity:	107/541 - (19%)
Similarity:	196/541 - (36%)	Gaps:	122/541 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVIQVP-----LS 79
            |||.........|..:..|:...:..||:|...|.:||.|..   ..||:.|...:.|     |.
plant     6 GSSSQKPHAMCIPYPAQGHINPMLKLAKLLHARGFHVTFVNT---DYNHRRILQSRGPHALNGLP 67

  Fly    80 KEEAQQMSDTI---GAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMN--DRVRDLYLNRGNKF 139
            ....:.:.|.:   ...:|.|       :|::.|          .|:.|  ...:||.|...:..
plant    68 SFRFETIPDGLPWTDVDAKQD-------MLKLID----------STINNCLAPFKDLILRLNSGS 115

  Fly   140 DL-----VISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAGISN----PAE 195
            |:     :||...|: |.:..|.::..||::|.|.....|:       |.:.|..:..    |.:
plant   116 DIPPVSCIISDASMS-FTIDAAEELKIPVVLLWTNSATALI-------LYLHYQKLIEKEIIPLK 172

  Fly   196 GSKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEML------KNTSLVF 254
            .|.  ..::.|.:.:..:     ..:.:.:.:::...|...:|:.|..|.:|      |..|.:|
plant   173 DSS--DLKKHLETEIDWI-----PSMKKIKLKDFPDFVTTTNPQDPMISFILHVTGRIKRASAIF 230

  Fly   255 FSSHAASEG----PIRPNVPSAIEIGGIQIKDKPD--------PLPQNIAE-------FLGNATD 300
            .::....|.    .:|..:|....:|..||.:..:        .|..|:.|       :|....:
plant   231 INTFEKLEHNVLLSLRSLLPQIYSVGPFQILENREIDKNSEIRKLGLNLWEEETESLDWLDTKAE 295

  Fly   301 GAIL-LSLGSNVQGKHLNPDTVAKMFNVLSKLKERVIWKWE------DQENTPG------KSANI 352
            .|:: ::.||...   |..:.:.:....|::..:..:|...      |....|.      |:..:
plant   296 KAVIYVNFGSLTV---LTSEQILEFAWGLARSGKEFLWVVRSGMVDGDDSILPAEFLSETKNRGM 357

  Fly   353 LYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKS-GFGLTL 416
            |...|..|:.:|:||.|..|:.|.|.....||.|.|.||:..|.||||..|.....:. |.|:.:
plant   358 LIKGWCSQEKVLSHPAIGGFLTHCGWNSTLESLYAGVPMICWPFFADQLTNRKFCCEDWGIGMEI 422

  Fly   417 SLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPL 481
            ......|:  .|.:::.|.:.:..:|:              ||..:.|...      |....:|.
plant   423 GEEVKRER--VETVVKELMDGEKGKRL--------------REKVVEWRRL------AEEASAPP 465

  Fly   482 VHMSFI----AANNIDICFLI 498
            :..|::    ..|.:..|..|
plant   466 LGSSYVNFETVVNKVLTCHTI 486

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	104/531 (20%)
Ugt37A3	NP_650229.2	UDPGT	37..526	CDD:278624	103/524 (20%)
UGT85A4	NP_177950.1	Glycosyltransferase_GTB-type	5..480	CDD:415824	105/533 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000