DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37A3 and UGT88A1

DIOPT Version :9

Sequence 1:	NP_650229.2	Gene:	Ugt37A3 / 41574	FlyBaseID:	FBgn0038083	Length:	530	Species:	Drosophila melanogaster
Sequence 2:	NP_566550.1	Gene:	UGT88A1 / 820900	AraportID:	AT3G16520	Length:	462	Species:	Arabidopsis thaliana

Alignment Length:	517	Identity:	100/517 - (19%)
Similarity:	187/517 - (36%)	Gaps:	121/517 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 GANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNITVIQVPLSKEEAQQMSD 88
            |...:.|:|:....||:..:...|.:.....::::..:|.|.......|...:  |...:...|.
plant     2 GEEAIVLYPAPPIGHLVSMVELGKTILSKNPSLSIHIILVPPPYQPESTATYI--SSVSSSFPSI 64

  Fly    89 TI-----------GAMSKNDNSNMALSLLRMSD----------QMDFMIRKNAETLMNDRVRDLY 132
            |.           .:.|::.:.::.|.:|..|:          ..:|.:|..........|.|:
plant    65 TFHHLPAVTPYSSSSTSRHHHESLLLEILCFSNPSVHRTLFSLSRNFNVRAMIIDFFCTAVLDI- 128

  Fly   133 LNRGNKFDLVISGYFMNDFQLG---FARKVNAPVIVLATMPPNHLLN-PLIGNPLEVSYAGISNP 193
                 ..|.....||.  :..|   .|.....|.|. .|.|..:|.: |.:..|      |:. |
plant   129 -----TADFTFPVYFF--YTSGAACLAFSFYLPTID-ETTPGKNLKDIPTVHIP------GVP-P 178

  Fly   194 AEGS---KAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFF 255
            .:||   ||| .:|....|...:.||              |::..:...:....:.|:|.::...
plant   179 MKGSDMPKAV-LERDDEVYDVFIMFG--------------KQLSKSSGIIINTFDALENRAIKAI 228

  Fly   256 SSHAASEG--PIRPNVPSAIEIGGIQIKDKP-----------DPLPQNIAEFL--GN----ATDG 301
            :.......  ||.|.:     :.| :|:|:.           |..|:....||  |:    :.:.
plant   229 TEELCFRNIYPIGPLI-----VNG-RIEDRNDNKAVSCLNWLDSQPEKSVVFLCFGSLGLFSKEQ 287

  Fly   302 AILLSLGSNVQGKHL-----NPDTVAKM-FNVLSKLKERVIWKWEDQENTPGKSANILYSKWLPQ 360
            .|.:::|....|:..     ||..:.|. .::.|.|.|..:.:.||:        .::...|.||
plant   288 VIEIAVGLEKSGQRFLWVVRNPPELEKTELDLKSLLPEGFLSRTEDK--------GMVVKSWAPQ 344

  Fly   361 DDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKP 425
            ..:|.|..:..|:.|.|...|.|:...|.||::.|::|:|..| ..|:.....:.:|:
plant   345 VPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFN-RVMIVDEIKIAISM------- 401

  Fly   426 FQEAILEILSNPQYAERVKSF--STLYRDRPMTARESFLYWTEYVIRHHGAAH------LQS 479
             .|:....:|:.:..:||:..  ....|:|.|..:.:    .|..:...|::|      |||
plant   402 -NESETGFVSSTEVEKRVQEIIGECPVRERTMAMKNA----AELALTETGSSHTALTTLLQS 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	egt	1..490	CDD:223071	100/517 (19%)
Ugt37A3	NP_650229.2	UDPGT	37..526	CDD:278624	97/504 (19%)
UGT88A1	NP_566550.1	PLN03004	1..451	CDD:178581	97/508 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000