Protein Alignment Ugt37A3 and ugt2a6

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001138283.1
• Gene: ugt2a6 / 797211
• ZFINID: ZDB-GENE-081104-3
• Length: 529
• Species: Danio rerio
• Alignment Length: 531
• Identity: 144/531 - (27%)
• Similarity: 236/531 - (44%)
• Gaps: 76/531 - (14%)

  Fly    37 SHLIIQMSAAKVLAENGHNVTV-VTVLKPVVNHK-----NITVIQVPLSKEEAQQ---------M 86
            ||........:.|.:..|:||| |....|.|.|.     ...|.:|.:.||....         |
Zfish    31 SHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEVVDYLWIHFHELWM 95

  Fly    87 SDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLY------LNRGNKFDLVISG 145
            ::||....|.......:||.|...:              :.|:.|:      ..|.:.:|::.|.
Zfish    96 NETISTYEKTLEVWQLMSLFRAHSE--------------ELVKGLFDVGLLKTLRDSNYDVLFSD 146

  Fly   146 YFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGN-PLEVSYAGISNPAEG--SKAVTFQRRLS 207
            ..| .|....|:|:|.|.::...:.....|..|.|. |:..||...: .|:|  :..::|..|:.
Zfish   147 LTM-PFSDLMAQKLNIPHVLSMRISFASALERLCGQMPVPQSYVPAA-VAQGHLTDRMSFTERVE 209

  Fly   208 SYM---------QSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEG 263
            :.:         |......|.|:        |.|:.|....|   .|.:..|.:....::...|.
Zfish   210 NMLLYITHTAMFQLTTKFTFDHI--------YAEISGEPTTM---CETIGKTDIWLIRTYWDFEY 263

  Fly   264 PIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GAILLSLGSNVQGKHLNPDTVAKMFNV 327
            | ||..|:...:||:|.| ...||.:.:.||:.::.| |.::.||||.:  |:|.......:...
Zfish   264 P-RPFPPNFKFVGGLQCK-PAKPLAKELEEFVQSSGDHGIVVFSLGSMI--KNLTVQKANTIAAA 324

  Fly   328 LSKLKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPM 391
            |.::.::|:|::..:  ||...| |.....|:||:|:|.||..|.||.|.|..|:.|:.|||.||
Zfish   325 LGQISQKVVWRYSGK--TPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPM 387

  Fly   392 LSLPVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMT 456
            :.||:|.|||.|...:...|..:.|...|||.|...:|:..:|:||.|.|.:...|.::.|:||.
Zfish   388 VGLPLFGDQPDNLMHLKSKGAAVVLDFFTLESKDLVDALKTVLNNPSYKESIMRLSRIHHDQPMK 452

  Fly   457 ARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFL----VQFIY 517
            ..:..:||.|:|:|:.||.||:.....:|:...:.:|:.    ..|:|:..||.||    ..|::
Zfish   453 PLDQAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVA----AFLLSITALITFLWVKACCFLF 513

  Fly   518 RRFISKPKKEK 528
            ||.:.|.:.|:
Zfish   514 RRCVRKTRPER 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	122/461 (26%)
ugt2a6	NP_001138283.1	UDPGT	21..519	CDD:278624	142/524 (27%)