Protein Alignment Ugt37A3 and ugt1b4

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001166239.2
• Gene: ugt1b4 / 795050
• ZFINID: ZDB-GENE-080227-13
• Length: 533
• Species: Danio rerio
• Alignment Length: 575
• Identity: 143/575 - (24%)
• Similarity: 258/575 - (44%)
• Gaps: 91/575 - (15%)

  Fly     1 MVLRVEKFLLLAIAIGAVMGS------SQGANILG--LFPSLSPSHLIIQMSAAKVLAENGHNVT 57
            |.|.:...:::.:.:|.|..:      |:.::..|  |...:..||.....:.|:.:...||  |
Zfish     1 MTLTMHLGVIICLVVGVVCSAVVDQKLSRNSSWTGKLLVVPMDGSHWTGVKAVAEEMGRRGH--T 63

  Fly    58 VVTVLKPV----------------VNHKNITVIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLL 106
            |:.|:..:                |.:|...:.|:.:  |...:::.:..::.|...|.|    .
Zfish    64 VIVVIPEISMRLGPGKHYITKKFPVQYKQDLINQIMV--EHVNEVAASEQSLLKTVTSIM----Y 122

  Fly   107 RMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLG--FARKVNAPVIVLATM 169
            |....:|..| ..:|:|..::....:| |...||.|::...|   .:|  .|..::.|.:.:
Zfish   123 RFGKIIDHFI-STSESLFQEQELIEFL-RDQNFDAVLTNPAM---PMGAILAYNLSVPAVYM--- 179

  Fly   170 PPNHLLNPLIGNPLEVSYAGISNP--------AEGSKAVTFQRR--------LSSYMQSLGFGVF 218
                    |.|...|.......||        .:.|..:||..|        |...|..|..|.|
Zfish   180 --------LRGIMCESKATACPNPPSYIPRFFTQISDRMTFSERVINTLVSLLEPLMCRLMLGSF 236

  Fly   219 SHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDK 283
               .|..::..:::|        ..:|:|...::.........|.| :|.:|:.|.||||..:.|
Zfish   237 ---EEMTSKFLHRDV--------SITEILSTAAVWLMRYDFTLEFP-KPLMPNMITIGGINCEVK 289

  Fly   284 PDPLPQNIAEFL-GNATDGAILLSLGSNVQGKHLNPDTVAKM-FNVLSKLKERVIWKW--EDQEN 344
             :||.:.:.||: |:...|.::.||||.|...   |...|.: |...|.:.:||:|::  |...|
Zfish   290 -NPLTKEVEEFVNGSGEHGIVVFSLGSLVSSM---PKEKADIFFKAFSMIPQRVLWRYTGEIPNN 350

  Fly   345 TPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVK 409
            .|   .|:...|||||:|:|.||..:.||.|.|..||.|...||.||:.||:|.||..|.:.:..
Zfish   351 VP---ENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQADNVHRVAT 412

  Fly   410 SGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGA 474
            .|.|:.||:..:..:...:|:..:::|..|.::::..|.::.|||:...:..::|||:|:||.||
Zfish   413 RGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTEFVMRHKGA 477

  Fly   475 AHLQSPLVHMSFIAANNIDIC-FLIFVILVSVLVLIKFLVQFIYRRFISKPKKEK 528
            .||:.....::::..:::|:. |::.::|:..|.::| .....:||...|.:|.|
Zfish   478 DHLRPAAHELNWLQYHSLDVIGFMLLIVLIVTLAMLK-CCSLCWRRCCRKTQKRK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/478 (25%)
ugt1b4	NP_001166239.2	UDPGT	35..529	CDD:278624	136/537 (25%)