Protein Alignment Ugt37A3 and ugt2b6

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001170806.3
• Gene: ugt2b6 / 792506
• ZFINID: ZDB-GENE-100402-4
• Length: 527
• Species: Danio rerio
• Alignment Length: 557
• Identity: 141/557 - (25%)
• Similarity: 264/557 - (47%)
• Gaps: 79/557 - (14%)

  Fly    13 IAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLKPVVNHKNIT----- 72
            :::.:::.:.:..|:|..|  ...||.|......:.|.:.||:|||:.....:....|.:
Zfish     8 LSLLSLLSAGECGNVLVWF--TEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKANASDRFSY 70

  Fly    73 -VIQVPLSKEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLN-- 134
             ...|.:.::|.:...:..          :..||..| ||::|...::.......:::|:.::
Zfish    71 QPFNVSMDEQEMKVFIEEF----------LYFSLYEM-DQLNFFQMQSKVYEFTSKLQDMSISYC 124

  Fly   135 -------------RGNKFDLVISG--YFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGN-PL 183
                         |.:|||:|.|.  |..:|.   .|.::|.|::........|....:.|. |.
Zfish   125 DGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDI---VAEELNVPLVYTFRFSLAHAAERMCGQIPA 186

  Fly   184 EVSYAGISNPAEGSK---AVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSE 245
            ..||.    |...||   .::|..|:.:.:..|....|:..:.::..|:|.|.:|   :...|.|
Zfish   187 PPSYV----PGAMSKLTDRMSFTERIYNMLFYLSQDAFAVFAWKKIDNYYTEYFG---RPTSYCE 244

  Fly   246 MLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKPDPLPQNIAEFL-GNATDGAILLSLGS 309
            |:....:....::...|.| ||.||:...|||:.. ....|||:::.||: .:..||.::.:|||
Zfish   245 MMGRADIWLIRTYWDFEFP-RPFVPNFKYIGGLHC-TPAKPLPKDMEEFVQSSGDDGIVVFTLGS 307

  Fly   310 NVQGKHLNPDTVA-KMFNVLSKLKERVIWKW-EDQENTPGKSANILYSKWLPQDDILAHPNIKLF 372
            .| ||  .|..:: ::.:.|:::.::|:|:: .::.:|.|::..|.  ||:||:|:|.||..:.|
Zfish   308 LV-GK--VPKEISNRIASALAQIPQKVLWRYGGEKPDTLGENTRIY--KWIPQNDLLGHPKTRAF 367

  Fly   373 INHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTL-SLLTLEEKPFQEAILEILSN 436
            |.|.|..||.|:.|||.||:.:|:|.|||.|...|...|..:.: |:.:::.:...:.:..::::
Zfish   368 ITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVIND 432

  Fly   437 PQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNID----ICFL 497
            |.|.|.....|.::.||||...:..::|.|:|:|:.||.||:        :.|:|:.    .|..
Zfish   433 PSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKGAKHLR--------VEAHNLTWYQYHCLD 489

  Fly   498 IFVILVSVLVLIKF----LVQFIYRR--FISKPKKEK 528
            :|..|.:||.|:.:    :.:|...|  |.||.|.:|
Zfish   490 VFAFLTTVLTLVLYICFKMAKFFIMRCCFRSKRKSKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	118/469 (25%)
ugt2b6	NP_001170806.3	None