Protein Alignment Ugt37A3 and ugt2a5

DIOPT Version :10

• Sequence 1: NP_650229.2
• Gene: Ugt37A3 / 41574
• FlyBaseID: FBgn0038083
• Length: 530
• Species: Drosophila melanogaster
• Sequence 2: NP_001070111.2
• Gene: ugt2a5 / 767705
• ZFINID: ZDB-GENE-060929-796
• Length: 532
• Species: Danio rerio
• Alignment Length: 528
• Identity: 141/528 - (26%)
• Similarity: 240/528 - (45%)
• Gaps: 70/528 - (13%)

  Fly    37 SHLIIQMSAAKVLAENGHNVTV-VTVLKPVVNHK-----NITVIQVPLSKEEAQ-QMSDTIGAMS 94
            ||........:.|.:..|:||| |....|.|.|.     ...|.:|.:.||||. .|.|.|...:
Zfish    31 SHWHNMRPVIEALVDKNHSVTVLVGSSSPTVPHTQKERFEYHVFKVNMEKEEADAAMRDMIHLFT 95

  Fly    95 KNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVR--DLYLN-----------RGNKFDLVISGY 146
             ||.:        ...:.:|::.|    :|:..|.  |:|..           |.:.:|::.|..
Zfish    96 -NDTA--------AKYEGEFVMWK----VMSKFVEFGDVYFRGLFDVGLLKTLRDSNYDVLFSDP 147

  Fly   147 FMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGN-PLEVSYAGISNPAEG-----SKAVTFQRR 205
            .| .|....|:|:|.|.::.......:....|.|. |...||.    ||..     :..::|..|
Zfish   148 MM-PFSDLMAQKLNIPQVISMRATFAYAAERLCGQMPAPPSYV----PAVALTDHLTDRMSFMER 207

  Fly   206 LSSYM----QSLGFGVFSHLSERRNRNWYKEVYGNDPKMPEYSEMLKNTSLVFFSSHAASEGPIR 266
            :.:.:    .|:.|.:.:..:   ...:|.|:.|....|   .|.:....:....::...|.| |
Zfish   208 VENMLLYIVHSIAFPLVATFT---FDGYYSEILGKPTTM---CETMGKVDICLIRTYWDFEYP-R 265

  Fly   267 PNVPSAIEIGGIQIKDKPDPLPQNIAEFLGNATD-GAILLSLGSNVQGKHLNPDTVAKMFNVLSK 330
            |..|:...:||:..| ...||.:.:.||:.::.| |.::.||||.:  |:|..:....:...|.:
Zfish   266 PFPPNFKFVGGLHCK-PAKPLSKELEEFVQSSGDHGVVVFSLGSMI--KNLTSERANTIAAALGQ 327

  Fly   331 LKERVIWKWEDQENTPGKSA-NILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSL 394
            :.::|:|::..:  ||...| |.....|:||:|:|.||..|.||.|.|..|:.|:.|||.||:.|
Zfish   328 IPQKVVWRYSGK--TPETLAPNTKIYDWIPQNDLLGHPKTKAFITHGGTNGLYEAIYHGVPMVGL 390

  Fly   395 PVFADQPRNANAMVKSGFGLTLSLLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARE 459
            |:|.|||.|...:...|..:.|.:.|:..|...:|:..:::||.|.|.:...|.::.|:||...:
Zfish   391 PLFGDQPDNLLHIKTKGAAVVLDIHTMGSKDLVDALKAVVNNPSYKESIMRLSRIHHDQPMKPLD 455

  Fly   460 SFLYWTEYVIRHHGAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFL----VQFIYRRF 520
            ..:||.|:|:|:.||.||:.....:|:...:.:|:.    ..|:|:..||.||    ..|::||.
Zfish   456 QAVYWIEFVMRNKGAKHLRVQAHELSWYQYHCLDVA----AFLLSITALITFLWVKACCFLFRRC 516

  Fly   521 ISKPKKEK 528
            :.|.:.|:
Zfish   517 VRKTRPER 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37A3	NP_650229.2	GT1_Gtf-like	25..464	CDD:340817	119/458 (26%)
ugt2a5	NP_001070111.2	UDPGT	21..519	CDD:278624	139/521 (27%)